中国药品标准
中國藥品標準
중국약품표준
DRUG STANDARDS OF CHINA
2014年
2期
117-119
,共3页
林吉恒%肖璜%马仕洪%胡昌勤
林吉恆%肖璜%馬仕洪%鬍昌勤
림길항%초황%마사홍%호창근
黑曲霉%孢子悬液%贮存期验证%验证方法
黑麯黴%孢子懸液%貯存期驗證%驗證方法
흑곡매%포자현액%저존기험증%험증방법
Aspergillus niger%spore suspension%verification of the storage period%verified method
目的：对贮存期的黑曲霉孢子悬液的质量进行考察和研究。方法：采用计数法及药敏实验对黑曲霉孢子悬液在贮存期的变化进行分析。结果：低温（4℃）保存6个月内黑曲霉孢子悬液菌落计数结果稳定，药物敏感性未出现变化，符合药典的规定。结论：在实验中，验证过的储存期内黑曲霉孢子悬液可直接稀释使用。
目的：對貯存期的黑麯黴孢子懸液的質量進行攷察和研究。方法：採用計數法及藥敏實驗對黑麯黴孢子懸液在貯存期的變化進行分析。結果：低溫（4℃）保存6箇月內黑麯黴孢子懸液菌落計數結果穩定，藥物敏感性未齣現變化，符閤藥典的規定。結論：在實驗中，驗證過的儲存期內黑麯黴孢子懸液可直接稀釋使用。
목적：대저존기적흑곡매포자현액적질량진행고찰화연구。방법：채용계수법급약민실험대흑곡매포자현액재저존기적변화진행분석。결과：저온（4℃）보존6개월내흑곡매포자현액균락계수결과은정，약물민감성미출현변화，부합약전적규정。결론：재실험중，험증과적저존기내흑곡매포자현액가직접희석사용。
Objective:To investigate and study the quality of Aspergillus niger spore suspension.Methods:By counting and suscepti-bility test to conduct the experiments.Results: The cryopreservation ( 4 ℃) of Aspergillus niger spore suspension within 6 months showed no significant changes in drug sensitivity and counting results of colonies were stable , conformed to the standard of Chinese Pharmacopeia.Conclusion:Aspergillus niger spore suspension can be diluted directly in the specific experiment during the the storage that was verified.
