中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2013年
7期
686-690
,共5页
彭岳文%刘芳%古振%李文华%贺常仁%章喆%李捷一
彭嶽文%劉芳%古振%李文華%賀常仁%章喆%李捷一
팽악문%류방%고진%리문화%하상인%장철%리첩일
25羟维生素D/25(OH)D%维生素D缺乏%维生素D不足%骨密度/BMD
25羥維生素D/25(OH)D%維生素D缺乏%維生素D不足%骨密度/BMD
25간유생소D/25(OH)D%유생소D결핍%유생소D불족%골밀도/BMD
25-hydroxyvitamin D/25 (OH)D%Vitamin D deficiency%Vitamin D insufficiency%Bone mineral density/BMD
目的 通过测定269名岳阳地区50岁以上人群血清25羟维生素D(25(OH)D)和骨密度(BMD)水平,分析岳阳地区50岁以上人群的维生素D(VitD)状况,并探讨其与BMD的关系.方法 采集受试者的血清后,用电化学发光法测定血清25(OH)D水平,并同时应用双能X线吸收仪测定腰椎及髋部BMD.结果 所有受试者中,VitD严重缺乏者占24.2％,缺乏者占45.0％,不足者占24.5％,充足者占6.3％.男、女性受试者的25(OH)D水平、腰椎及髋部的BMD间有统计学差异(P＜0.001),男性高于女性.男性各年龄段间25(OH)D水平及各部位BMD无统计学差异(P =0.101、P=0.261,0.055,0.170,0.108,0.051)；女性各年龄段之间25(OH)D水平及腰椎BMD无统计学差异(P =0.364,0.063)；髋部BMD有统计学差异(P＜0.001),随着年龄的增长而逐步减低.男性受试者中,不同25(OH)D水平组间股骨颈、转子间区及整髋BMD无统计学差异(P=0.076,0.425,0.122)；腰椎、大转子区BMD水平间有统计学差异(P=0.027,0.017),VitD充足组腰椎BMD高于其他各组(P =0.005,0.025,0.009)；不足组、严重缺乏组大转子区BMD高于缺乏组(P =0.021,0.005).女性受试者中,不同25(OH)D水平组各部位BMD均无统计学差异(P=0.616,0.739,0.559,0.608,0.641).结论 在湖南岳阳地区50岁以上人群存在严重的维生素D缺乏及不足；对于维生素D状况与骨密度之间可能无直接关联,需加大样本量进一步观察.
目的 通過測定269名嶽暘地區50歲以上人群血清25羥維生素D(25(OH)D)和骨密度(BMD)水平,分析嶽暘地區50歲以上人群的維生素D(VitD)狀況,併探討其與BMD的關繫.方法 採集受試者的血清後,用電化學髮光法測定血清25(OH)D水平,併同時應用雙能X線吸收儀測定腰椎及髖部BMD.結果 所有受試者中,VitD嚴重缺乏者佔24.2％,缺乏者佔45.0％,不足者佔24.5％,充足者佔6.3％.男、女性受試者的25(OH)D水平、腰椎及髖部的BMD間有統計學差異(P＜0.001),男性高于女性.男性各年齡段間25(OH)D水平及各部位BMD無統計學差異(P =0.101、P=0.261,0.055,0.170,0.108,0.051)；女性各年齡段之間25(OH)D水平及腰椎BMD無統計學差異(P =0.364,0.063)；髖部BMD有統計學差異(P＜0.001),隨著年齡的增長而逐步減低.男性受試者中,不同25(OH)D水平組間股骨頸、轉子間區及整髖BMD無統計學差異(P=0.076,0.425,0.122)；腰椎、大轉子區BMD水平間有統計學差異(P=0.027,0.017),VitD充足組腰椎BMD高于其他各組(P =0.005,0.025,0.009)；不足組、嚴重缺乏組大轉子區BMD高于缺乏組(P =0.021,0.005).女性受試者中,不同25(OH)D水平組各部位BMD均無統計學差異(P=0.616,0.739,0.559,0.608,0.641).結論 在湖南嶽暘地區50歲以上人群存在嚴重的維生素D缺乏及不足；對于維生素D狀況與骨密度之間可能無直接關聯,需加大樣本量進一步觀察.
목적 통과측정269명악양지구50세이상인군혈청25간유생소D(25(OH)D)화골밀도(BMD)수평,분석악양지구50세이상인군적유생소D(VitD)상황,병탐토기여BMD적관계.방법 채집수시자적혈청후,용전화학발광법측정혈청25(OH)D수평,병동시응용쌍능X선흡수의측정요추급관부BMD.결과 소유수시자중,VitD엄중결핍자점24.2％,결핍자점45.0％,불족자점24.5％,충족자점6.3％.남、녀성수시자적25(OH)D수평、요추급관부적BMD간유통계학차이(P＜0.001),남성고우녀성.남성각년령단간25(OH)D수평급각부위BMD무통계학차이(P =0.101、P=0.261,0.055,0.170,0.108,0.051)；녀성각년령단지간25(OH)D수평급요추BMD무통계학차이(P =0.364,0.063)；관부BMD유통계학차이(P＜0.001),수착년령적증장이축보감저.남성수시자중,불동25(OH)D수평조간고골경、전자간구급정관BMD무통계학차이(P=0.076,0.425,0.122)；요추、대전자구BMD수평간유통계학차이(P=0.027,0.017),VitD충족조요추BMD고우기타각조(P =0.005,0.025,0.009)；불족조、엄중결핍조대전자구BMD고우결핍조(P =0.021,0.005).녀성수시자중,불동25(OH)D수평조각부위BMD균무통계학차이(P=0.616,0.739,0.559,0.608,0.641).결론 재호남악양지구50세이상인군존재엄중적유생소D결핍급불족；대우유생소D상황여골밀도지간가능무직접관련,수가대양본량진일보관찰.
