CAJ | 학술논문

目的了解河北省沧州市10～14岁学龄儿童干眼患病情况,并探讨干眼发病的相关危险因素.方法横断面研究.2011年3月至2012年10月,沧州眼科医院在沧州市单纯随机抽取40所学校作为调查点,对约7万名五、六年级学龄儿童整群随机抽样,抽取调查对象3150人.所有受检者均接受干眼症状、眼表疾病指数问卷调查及体征检查.依据目前公认的国内于眼诊断标准进行诊断,采用t检验、Pearson卡方检验、Logistic回归分析法对数据进行统计.结果共计3007人进入本次研究,应答率为95.46％.诊断为干眼的有858例,患病率为28.53％.其中男性489例,患病率为30.07％,女性369例,患病率为26.72％,男性高于女性.干眼组年龄、睑板腺功能分级、角结膜荧光染色均高于非干眼组;泪液分泌试验(Schirmer I test,SIT)、泪膜破裂时间(break-up time,BUT)均低于非于眼组(P＜0.05).干涩感、异物感、烧灼感、眼睑沉重感、分泌物多在干眼组与非干眼组差异有统计学意义(P＜0.05).干眼组眼表疾病指数评分总分高于非干眼组(t =-2.623,P=0.009).性别与挑食是干眼的危险因素(P＜0.05).结论沧州市10～14岁学龄儿童干眼患病率很高,且男性高于女性.家庭和社会应引起足够重视,引导儿童用眼卫生,均衡饮食,预防干眼的发生.
목적 료해하북성창주시10～14세학령인동간안환병정황,병탐토간안발병적상관위험인소.방법 횡단면연구.2011년3월지2012년10월,창주안과의원재창주시단순수궤추취40소학교작위조사점,대약7만명오、륙년급학령인동정군수궤추양,추취조사대상3150인.소유수검자균접수간안증상、안표질병지수문권조사급체정검사.의거목전공인적국내우안진단표준진행진단,채용t검험、Pearson잡방검험、Logistic회귀분석법대수거진행통계.결과 공계3007인진입본차연구,응답솔위95.46％.진단위간안적유858례,환병솔위28.53％.기중남성489례,환병솔위30.07％,녀성369례,환병솔위26.72％,남성고우녀성.간안조년령、검판선공능분급、각결막형광염색균고우비간안조;루액분비시험(Schirmer I test,SIT)、루막파렬시간(break-up time,BUT)균저우비우안조(P＜0.05).간삽감、이물감、소작감、안검침중감、분비물다재간안조여비간안조차이유통계학의의(P＜0.05).간안조안표질병지수평분총분고우비간안조(t =-2.623,P=0.009).성별여도식시간안적위험인소(P＜0.05).결론 창주시10～14세학령인동간안환병솔흔고,차남성고우녀성.가정화사회응인기족구중시,인도인동용안위생,균형음식,예방간안적발생.
Objective To obtain the data of the prevalence of dry eye in school children age of 10 to 14 years old in Cangzhou,Hebei,China.To investigate the relative risk factors of dry eye.Methods A cross-sectional study.From March 2011 to October 2012,40 schools including 70000 people of 5 and 6 grade school children were randomly selected as survey venues by Cangzhou Eye Hospital.Then,3150 people as the selected residents were enrolled,which was figured out through the random cluster sampling procedure.Every participant completed dry eye questionnaire,the ocular surface disease index (OSDI) and a series of examination.The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria.The t test,Pearson 2 test and Logistic regression were used for analysis.Results Of 3007 residents finally took part in this study,and the inclusion ratio was 85.7％; 858 individuals,including 489 men and 369 women,were diagnosed as dry eye,and the prevalence rate was 28.53％.The prevalence of dry eye in the male (30.07％) was higher than that of female (26.72％).The age,Meibomian glands functional classification and Grading of corneal and conjunctival staining were higher in dry eye group.Meanwhile,the Schirmer I test (S I T) and break-up time (BUT) were lower in dry eye group (P ＜0.05).There were significant differences between dry eye group and non-dry eye group including sensation of dryness,foreign body sensation,burning sensation,eyelid heaviness,more secretions (P ＜0.05).The score of OSDI in dry eye children was significantly higher than that in non-dry eye individuals (t =-2.623,P =0.009).The relative risk factors of dry eye were gender and choosy in food.Conclusions The prevalence of dry eye is fairly high in school children age of 10 to 14 years old in Cangzhou,which in male is higher than that in the female.Family and community should pay sufficient attention to conduct children's eye health and prepare a balanced diet,to prevent the occurrence of dry eye.