CAJ | 학술논문

目的分析羧甲基纤维素钠眼液对白内障超声乳化摘除术后干眼的治疗效果。方法选取2013年12月~2014年2月于我院行白内障超声乳化摘除术的年龄相关性白内障患者106例(129眼)，随机分为对照组和治疗组，其中治疗组加用羧甲基纤维素钠眼液。对患者分别行术前及术后1d、1w、1个月泪膜破裂时间(BUT)、角膜荧光染色(FL)检查、和自觉症状评分。结果白内障术后干眼主观症状增加、BUT明显缩短、FL明显增多。至术后1个月，对照组干眼主观症状、BUT与术前相比仍具有统计学意义(约0.05)。治疗组术后1w干眼主观症状、BUT和FL已接近术前水平(跃0.05)，且术后各时间点较对照组干眼主观症状更轻、BUT更长、FL更少(约0.05)。结论白内障超声乳化手术后早期使用羧甲基纤维素钠眼液可有效改善干眼症状、恢复泪膜稳定性，缩短眼表功能修复时间。
목적분석최갑기섬유소납안액대백내장초성유화적제술후간안적치료효과。방법선취2013년12월~2014년2월우아원행백내장초성유화적제술적년령상관성백내장환자106례(129안)，수궤분위대조조화치료조，기중치료조가용최갑기섬유소납안액。대환자분별행술전급술후1d、1w、1개월루막파렬시간(BUT)、각막형광염색(FL)검사、화자각증상평분。결과백내장술후간안주관증상증가、BUT명현축단、FL명현증다。지술후1개월，대조조간안주관증상、BUT여술전상비잉구유통계학의의(약0.05)。치료조술후1w간안주관증상、BUT화FL이접근술전수평(약0.05)，차술후각시간점교대조조간안주관증상경경、BUT경장、FL경소(약0.05)。결론백내장초성유화수술후조기사용최갑기섬유소납안액가유효개선간안증상、회복루막은정성，축단안표공능수복시간。
Objective To investigate the effect of carboxymethylcellulose sodium eye drops on the age-related cataract patients with dry eye after phacoemulsification. Methods A total of 106 patients underwent operation (129 eyes) with age-related cataract referred to our hospital from December 2013 to February 2014 were enrol ed in the study. Patients were randomly divided the treatment group and control group. The treatment group was received carboxymethylcellulose sodium eye drops therapy. Tear break-up time, cornea fluorescein staining were measured, as wel as subjective symptoms were graded before and 1d, 1w, 1m after phacoemulsification and intraocular lens implantation. Results The subjective symptoms were worse, tear break-up time was shorter, and cornea fluorescein staining on epithelium was more commonly seen post-operation as compare to pre-operation. The subjective symptoms grade and tear break-up time were stil abnormal in the control group 1m post-operation ( <0.05). However, the subjective symptoms grade, tear break-up time and cornea fluorescein staining on epithelium 1w post-operation was similar to that pre-operation conditions ( >0.05) , and al the post-opertation index were bet er in the treatment group than that in control group ( <0.05). Conclusion The carboxymethylcellulose sodium eye drops could ef iciently relieve the symptoms of dry eye and maintain the tear film stable for the patients underwent phacoemulsification.