CAJ | 학술논문

目的了解2012年该院患者送检血液、痰液、尿液等标本中分离出病原菌分布特点及耐药情况。方法收集2012年临床标本中分离的病原菌，采用全自动分析仪和API进行鉴定和药敏试验，采用WHONET5．6进行分析。结果临床分离的病原菌3454株中，革兰阳性菌占36％，革兰阴性菌占64％，专性厌氧菌占1％。耐甲氧西林金黄色葡萄球菌检出率分别为33％，耐万古霉素肠球菌检出率为1．6％。在肠杆菌科细菌中，产超广谱β-内酰胺酶（ESBLs）大肠埃希菌及肺炎克雷伯菌的检出率分别为60．6％及35．8％。非发酵菌以鲍曼不动杆菌和铜绿假单胞菌为主，耐药率高。结论医院感染的病原菌种类在不断增加；分离的病原菌耐药现象较普遍。持续做好细菌耐药监测工作，对指导临床合理使用抗菌药物有重要意义。
목적료해2012년해원환자송검혈액、담액、뇨액등표본중분리출병원균분포특점급내약정황。방법수집2012년림상표본중분리적병원균，채용전자동분석의화API진행감정화약민시험，채용WHONET5．6진행분석。결과림상분리적병원균3454주중，혁란양성균점36％，혁란음성균점64％，전성염양균점1％。내갑양서림금황색포도구균검출솔분별위33％，내만고매소장구균검출솔위1．6％。재장간균과세균중，산초엄보β-내선알매（ESBLs）대장애희균급폐염극뢰백균적검출솔분별위60．6％급35．8％。비발효균이포만불동간균화동록가단포균위주，내약솔고。결론의원감염적병원균충류재불단증가；분리적병원균내약현상교보편。지속주호세균내약감측공작，대지도림상합리사용항균약물유중요의의。
Objective To investigate the distribution and resistance of clinical isolates obtained from the second affiliated hospi-tal of Chongqing medical university in 2012 .Methods The bacteria strains isolated from clinics were collected .Identification and drug susceptibility test were performed by automatic analysis system and API manual identification system .The date was analyzed according with software WHONET 5 .6 .Results A total of 3 454 bacterial isolates were obtained ,which included 36% gram-posi-tive strains ,64% gram-negative strains and 1% Anaerobic bacteria .The detection rates of methicillin-resistant S .aures was 33% , the detection rate of vancomycin -resistant enterococci was 1 .6% .In enterobacteriaceae ,ESBLs producing strains accounted for 60 .6% and 35 .8% in E .coil and K .pneumonia respectively .The drug resistance of A .baumannii and P .aeruginosa was increased . Conclusion Drug resistance of bacterial isolated from our hospital is universal .Drug monitoring data is important for clinical treat-ment .