CAJ | 학술논문

目的观察锯叶棕果实提取物（SPE）联合坦索洛新治疗良性前列腺增生症（BPH）的疗效。方法将87例BPH患者随机分为治疗组（45例）与对照组（42例）。治疗组口服SPE联合坦索洛新，对照组口服坦索洛新，均连续治疗8周，观察治疗前后残余尿量（RU ）、最大尿流率（Qmax ）、国际前列腺症状评分（IPSS ）以及前列腺体积。结果对照组治疗后 RU、Qmax、IPSS较治疗前均有明显改善，差异有统计学意义（P＜0．05）；前列腺体积比较差异无统计学意义（P＞0．05）；治疗组的RU、Qmax、IPSS及前列腺体积较治疗前差异有统计学意义（P＜0．05）。结论 SPE联合坦索洛新治疗BPH能有效改善患者症状、缩小前列腺体积、提高患者生活质量。
목적관찰거협종과실제취물（SPE）연합탄색락신치료량성전렬선증생증（BPH）적료효。방법장87례BPH환자수궤분위치료조（45례）여대조조（42례）。치료조구복SPE연합탄색락신，대조조구복탄색락신，균련속치료8주，관찰치료전후잔여뇨량（RU ）、최대뇨류솔（Qmax ）、국제전렬선증상평분（IPSS ）이급전렬선체적。결과대조조치료후 RU、Qmax、IPSS교치료전균유명현개선，차이유통계학의의（P＜0．05）；전렬선체적비교차이무통계학의의（P＞0．05）；치료조적RU、Qmax、IPSS급전렬선체적교치료전차이유통계학의의（P＜0．05）。결론 SPE연합탄색락신치료BPH능유효개선환자증상、축소전렬선체적、제고환자생활질량。
Objective To observe the clinical efficacy of the saw palmetto extract combined with tamsulosin for the treatment of benign prostatic hyperplasia .Methods 87 benign prostatic hyperplasia patients were randomly divided into treatment group (45 ca-ses) and control group (42 cases) .The treatment group were treated with saw palmetto extract 160mg twice a day combined with tamsulosin 20mg once a day for 8 weeks .The control group were treated with tamsulosin 20mg once a day for 8 weeks .We com-pared the residual urine volume (RU) ,maximum urinary flow rates (Qmax) ,International Prostate Symptom Score (IPSS) and vol-ume of the prostate (V) before and after the treatment .Results After 8 weeks medication ,there were significant differences of the RU ,Qmax and IPSS between before and after treatment in the control group (P<0 .05) .The volume of the prostate was not signif-icantly changed (P>0 .05) .The RU ,Qmax ,IPSS and the volume of the prostate in the treatment group were significantly changed after treatment(P<0 .05) .Conclusion Saw palmetto extract combined with tamsulosin for the treatment of benign prostatic hyper-plasia could effectively improve the patient′s symptoms ,diminish the prostate gland volume and improve the life quality of the pa-tients .