CAJ | 학술논문

目的评估入院时静息呼吸频率与全球急性冠状动脉事件注册评分系统（GRACE）评分在急性冠脉综合征（ACS）风险分层中的作用和价值。方法前瞻性的收集符合纳入标准的ACS患者，在入院时检测患者呼吸频率并进行GRACE评分，根据呼吸频率分级和GRACE评分分级进行分组，观察近期心血管疾病病死率。随访时间为30 d。结果死亡组呼吸频率明显高于存活组。Kapian-M eier生存曲线分析揭示呼吸频率和GRACE危险积分高者近期预后明显较差；多变量Cox比例风险模型表明GRACE危险积分和呼吸频率是ACS患者近期病死率的独立危险因素。结论入院时静息呼吸频率与GRACE评分联合对ACS患者危险分层具有重要的临床应用价值，可用于近期死亡风险预警。
목적평고입원시정식호흡빈솔여전구급성관상동맥사건주책평분계통（GRACE）평분재급성관맥종합정（ACS）풍험분층중적작용화개치。방법전첨성적수집부합납입표준적ACS환자，재입원시검측환자호흡빈솔병진행GRACE평분，근거호흡빈솔분급화GRACE평분분급진행분조，관찰근기심혈관질병병사솔。수방시간위30 d。결과사망조호흡빈솔명현고우존활조。Kapian-M eier생존곡선분석게시호흡빈솔화GRACE위험적분고자근기예후명현교차；다변량Cox비례풍험모형표명GRACE위험적분화호흡빈솔시ACS환자근기병사솔적독립위험인소。결론입원시정식호흡빈솔여GRACE평분연합대ACS환자위험분층구유중요적림상응용개치，가용우근기사망풍험예경。
Objective The aim of this study is to assess the value of respiratory rate and Global Registry of Acute Coronary E-vents(GRACE) scoring system in risk stratification with Acute Coronary Syndrome (ACS) .Methods This study included patients with ACS .They were grouped according to respiratory rate and GRACE score .The patients with ACS met the inclusion criteria were detected for respiratory rate and GRACE score at the time of admission ;the recent mortality of patients with ACS had been observed by follow -up .The follow -up time was 30 days .Results The respiratory rate in the death group were higher than that in the surviving group .The results revealed the higher the respiratory rate and GRACE risk score ,the worse the prognosis by using Kapian-Meier survival curve analysis .GRACE risk score and respiratory rate in patients with ACS were independent risk factors for recent cardiovascular mortality in multivariate Cox proportional hazard model .Conclusion The resting respiratory rate and GRACE score have important clinical value for risk stratification of ACS patients ,which could be used for the risk warning of recent death .