CAJ | 학술논문

目的分析脑胶质瘤在氢质子磁共振波谱（1H-MRS）和磁共振弥散张量成像（DTI）上的表现特点与病理级别相关性。方法将41例脑胶质瘤患者依照世界卫生组织（WHO）分级的方法将其分为两组：低级别胶质瘤和高级别胶质瘤，术前均行常规磁共振成像（MRI）、DTI及1H-MRS检查，测量患侧占位核心实质区与对侧镜像区表观弥散系数（ADC）、各向异性分数（FA）、胆碱复合物（Cho）、N-乙酰天冬氨酸（NAA）和肌酐（Cr）。结果高、低级别胶质瘤肿瘤实质区ADC值和 FA值与镜像区比较，差异有统计学意义（P＜0．05）；高、低级别胶质瘤之间的ADC值和FA值差异亦有统计学意义（P＜0．05）；胶质瘤实质区与对侧镜像区NAA/Cr、Cho/Cr比较，差异有统计学意义（P＜0．05）；高、低级别胶质瘤NAA/Cr、NAA/Cho比较，差异有统计学意义（P＜0．05）。结论高、低级别胶质瘤1H-MRS和DTI存在明显差异。
목적분석뇌효질류재경질자자공진파보（1H-MRS）화자공진미산장량성상（DTI）상적표현특점여병리급별상관성。방법장41례뇌효질류환자의조세계위생조직（WHO）분급적방법장기분위량조：저급별효질류화고급별효질류，술전균행상규자공진성상（MRI）、DTI급1H-MRS검사，측량환측점위핵심실질구여대측경상구표관미산계수（ADC）、각향이성분수（FA）、담감복합물（Cho）、N-을선천동안산（NAA）화기항（Cr）。결과고、저급별효질류종류실질구ADC치화 FA치여경상구비교，차이유통계학의의（P＜0．05）；고、저급별효질류지간적ADC치화FA치차이역유통계학의의（P＜0．05）；효질류실질구여대측경상구NAA/Cr、Cho/Cr비교，차이유통계학의의（P＜0．05）；고、저급별효질류NAA/Cr、NAA/Cho비교，차이유통계학의의（P＜0．05）。결론고、저급별효질류1H-MRS화DTI존재명현차이。
Objective To analyze the performance of the glioma in proton magnetic resonance spectroscopy (1H-MRS) and diffu-sion tensor imaging(DTI) ,and to explore the relationship between the characteristics and pathological grade .Methods The 41 ca-ses of glioma patients were divided into two groups according to the World Health Organization (WHO) classification method :the low-level group and the high-level group .The patients underwent conventional magnetic resonance imaging ,DTI and 1H-MRS ex-amination ,and the ipsilateral placeholder district and contralateral reference zones ADC ,FA ,Cho ,NAA and Cr values were meas-ured .Results The difference of ADC and FA values in solid area between the two groups was significant compared with the contra-lateral ones (P< 0 .05) .The difference of ADC and FA value of the gliomas between the two groups was also significant (P<0 .05) .The NAA/Cr and Cho/Cr values in the two groups of glioma tumor was significantly different compared with the contralat-eral ones (P<0 .05) .The NAA/Cr and NAA/Cho values of the gliomas between the two groups were also significantly different (P<0 .05) .Conclusion The performance of glioma in 1H-MRS and DTI between the two groups showed significantly different .