CAJ | 학술논문

目的探讨DWI及其ADC值在宫颈癌中的应用价值以及ADC值与肿瘤分级的相关性。方法对36例宫颈癌患者及10例非宫颈肿瘤患者的宫颈进行常规MRI扫描、DWI成像及增强扫描，宫颈癌病例根据病理分级分为高分化组、中分化组及低分化组，比较正常宫颈各层与宫颈癌各组病灶的表观弥散系数（apparent diffusion coefficient，ADC）值。结果正常宫颈ADC值显著高于宫颈癌的ADC值（P<0.01）,宫颈癌病例中低分化组与中分化及高分化组间的ADC值有差异（P<0.05）.结论 DWI及ADC值可有效的区分宫颈癌及正常宫颈，ADC值与宫颈癌的病理分级具有一定的相关性。
목적탐토DWI급기ADC치재궁경암중적응용개치이급ADC치여종류분급적상관성。방법대36례궁경암환자급10례비궁경종류환자적궁경진행상규MRI소묘、DWI성상급증강소묘，궁경암병례근거병리분급분위고분화조、중분화조급저분화조，비교정상궁경각층여궁경암각조병조적표관미산계수（apparent diffusion coefficient，ADC）치。결과정상궁경ADC치현저고우궁경암적ADC치（P<0.01）,궁경암병례중저분화조여중분화급고분화조간적ADC치유차이（P<0.05）.결론 DWI급ADC치가유효적구분궁경암급정상궁경，ADC치여궁경암적병리분급구유일정적상관성。
Objective To determine the value of diffusion-weighted MRI and the apparent diffusion coefficient(ADC ) of cervical cancer and the the correlation between tumor grades and ADC.Methods Conventional MRI and DWI were performed in 36 females with surgical y proven cervical cancer and 10 females with pathological y confirmed normal cervix .Al the cases of cervical cancer were divided into wel-differentiated, moderately differentiated and poorly differentiated. To compare the ADC value between the normal cervix and cervical cancer.Results The ADC values of cervical cancer were significantly lower than those of normal cervix.The ADC values of poorly differentiated group were significantly lower than those of moderately differentiated group and wel-differentiated group.Conclusion DWI and ADC can differentiate beteween normal and cancerous cervix.ADC value has some dependablity with the grade of cervical cancer.