CAJ | 학술논문

目的研究慢性心力衰竭患者中血浆脑钠肽水平检测的临床意义。方法总结2011年1月-2012年6月期间在双峰县人民医院检查的慢性心力衰竭患者40例病例资料，按照心脏功能分级分3级：Ⅱ级10例，Ⅲ级17例，Ⅳ级13例，所有患者均用免疫荧光法检测血浆脑钠肽水平，计算各组平均值水平并观察规律，所有患者均用超声检测左心室结构，分别统计左心室舒张末期内径、左心室收缩末期内径和左心室射血分数，统计学方法计算该检测指标与患者血浆脑钠肽水平的相关性。结果患者血浆脑钠肽水平随着心脏功能级别的增大而增大，与左心室舒张末期内径、左心室收缩末期内径正相关（r 1=0.75，r 2=0.80），与左心室射血分数负相关（r=-0.71）。结论慢性心力衰竭患者中血浆脑钠肽水平能反映出患者心脏功能分级情况，对该类疾病患者病情的评价具有一定的意义。
목적연구만성심력쇠갈환자중혈장뇌납태수평검측적림상의의。방법총결2011년1월-2012년6월기간재쌍봉현인민의원검사적만성심력쇠갈환자40례병례자료，안조심장공능분급분3급：Ⅱ급10례，Ⅲ급17례，Ⅳ급13례，소유환자균용면역형광법검측혈장뇌납태수평，계산각조평균치수평병관찰규률，소유환자균용초성검측좌심실결구，분별통계좌심실서장말기내경、좌심실수축말기내경화좌심실사혈분수，통계학방법계산해검측지표여환자혈장뇌납태수평적상관성。결과환자혈장뇌납태수평수착심장공능급별적증대이증대，여좌심실서장말기내경、좌심실수축말기내경정상관（r 1=0.75，r 2=0.80），여좌심실사혈분수부상관（r=-0.71）。결론만성심력쇠갈환자중혈장뇌납태수평능반영출환자심장공능분급정황，대해류질병환자병정적평개구유일정적의의。
Objective To study of chronic heart failure patients on plasma brain natriuretic peptide level detection and clinical signiifcance of. Methods In the hospital examination in patients with chronic heart failure in 40 cases with cardiac function classiifcation, divided into three groups:10 cases in grade II, 17 cases in gradeⅢ, 13 cases in gradeⅣ, all patients were using ultrasound in detecting left ventricular structure, were left ventricular end diastolic diameter, left ventricular end-diastolic diameter and left ventricular ejection fraction, statistics method to calculate the detection index and plasma level of brain natriuretic peptide in patients with correlation. Results The plasma level of brain natriuretic peptide in patients with cardiac functional level increases, and left ventricular end diastolic diameter, left ventricular end systolic diameter correlated ( r 1=0.75, r 2=0.80 ), and left ventricular ejection fraction ( r=-0.71 ) negative correlation. Conclusion The Chronic heart failure patients on plasma brain natriuretic peptide level to relfect the cardiac function of the patients with grade.