CAJ | 학술논문

目的探讨DSA下平阳霉素碘化油乳剂超选择性动脉栓塞治疗肝脏血管瘤的近、中期疗效。方法选取2003-2010年收治的23例肝脏血管瘤患者，采用平阳霉素+超液态碘化油制成乳剂行供血动脉栓塞治疗，观察术前及术后3、6个月患者的临床症状、肝功能变化及病灶大小变化情况。结果23例患者除2例因病灶较大行二次介入治疗外，余均行一次治疗。术后第3、6个月复查肝脏CT所有患者血管瘤供血动脉均明显较少，其内可见碘油沉积、积聚。术后3个月病灶直径平均缩小2.5 cm，术后6个月平均缩小4.0 cm。术前有症状的患者术后3个月临床症状基本消失，肝功能基本恢复正常。所有患者均采用超选择插管技术，术后未见严重肝功能损伤、胆囊坏死及其他因过量栓塞导致的并发症。结论肝脏血管瘤的DSA下超选择性动脉平阳霉素碘化油乳剂栓塞术是一种安全、有效且容易让患者接受的治疗方法，值得应用与推广。
목적탐토DSA하평양매소전화유유제초선택성동맥전새치료간장혈관류적근、중기료효。방법선취2003-2010년수치적23례간장혈관류환자，채용평양매소+초액태전화유제성유제행공혈동맥전새치료，관찰술전급술후3、6개월환자적림상증상、간공능변화급병조대소변화정황。결과23례환자제2례인병조교대행이차개입치료외，여균행일차치료。술후제3、6개월복사간장CT소유환자혈관류공혈동맥균명현교소，기내가견전유침적、적취。술후3개월병조직경평균축소2.5 cm，술후6개월평균축소4.0 cm。술전유증상적환자술후3개월림상증상기본소실，간공능기본회복정상。소유환자균채용초선택삽관기술，술후미견엄중간공능손상、담낭배사급기타인과량전새도치적병발증。결론간장혈관류적DSA하초선택성동맥평양매소전화유유제전새술시일충안전、유효차용역양환자접수적치료방법，치득응용여추엄。
Objective To investigate the short term and midterm efifcacy of pingyangmycin lipiodol emulsion through super selective arterial embolization for liver hemangioma. Methods A total of 23 people received my branch from 2003 to 2010 that were diagnosed as liver hemangioma were collected for the study.We treated them with pingyangmycin plus lipiodol ultra lfuid for arterial embolization. The clinical symptoms, hepatic function and lesions size of the patients were observed before and 3, 6 month after this treatment.Results People all accepted one time treatment except 2 patients received the second interventional therapy for large size of lesions. We observed that there is iodipin deposition and accumulation in the artery of liver hemangioma. The size of liver hemangioma in all patients was signiifcantly reduced 3 and 6 months after the operations, using CT to reexamine the liver. The hemangioma had average narrow of 2.5 centimeters 3 months after the operations, and it came to 4 centimeters when 6 months after the operations. Meanwhile, the people’s clinical symptoms had almost gone 3 months after the operations and the liver function had almost returned to normal. We used super-selective catheterization in all the patients and no severe hepatic injury, gallbladder necrosis, or other complications such as embolism for the drug overdose happened to them. Conclusion The operation for liver hemangioma using super selective arterial embolization via digital subtraction angiography (DSA) with pingyangmycin lipiodol emulsion should be applied and promoted and it is safe, effective and acceptable.