中华实验和临床感染病杂志(电子版)
中華實驗和臨床感染病雜誌(電子版)
중화실험화림상감염병잡지(전자판)
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2013年
3期
350-352
,共3页
刘大凤%何盛华%蔡林%周锐锋%张毅%岳翼%温贤敏%周晓飞%陈萍%王伟%李青峰
劉大鳳%何盛華%蔡林%週銳鋒%張毅%嶽翼%溫賢敏%週曉飛%陳萍%王偉%李青峰
류대봉%하성화%채림%주예봉%장의%악익%온현민%주효비%진평%왕위%리청봉
艾滋病%结核病%临床特征%预后
艾滋病%結覈病%臨床特徵%預後
애자병%결핵병%림상특정%예후
Acquired immunodeifcency syndrome%Tuberculosis%Clinical characteristics%Prognosis
目的分析四川地区TB/HIV双重感染者的特征。方法回顾性分析10年来本院收治的361例TB/HIV双重感染者的临床特征及预后。结果住院艾滋病患者中TB/HIV双重感染流行率为21.32%(361/1693),病死率为10.53%(38/361);其中78.67%(284/361)患者为肺结核,73.96%(267/361)患者为肺外结核,52.63%(190/361)患者为肺结核及肺外结核同时存在。临床类型以肺外结核为主(73.96%,267/361),继发性肺结核次之(47.37%,171/361),再次为结核性胸膜炎(23.55%,85/361),血型播散型肺结核亦不少见,原发性肺结核少见;最常见的肺外结核为淋巴结结核、结核性脑膜炎,其次是结核性腹膜炎、心包结核,尚存在骨结核、肠结核及盆腔结核;两个部位同时感染最常见(75.35%,272/361);其次是单一部位感染(58.73%,212/361),3个及以上部位感染亦较多见(16.90%,61/361);3个及以上部位感染者病死率最高(18.03%,11/61),几乎是单一部位及两个部位感染病死率的两倍。结论四川地区住院艾滋病患者中TB/HIV双重感染常见,结核多部位感染、肺外结核、肺结核与肺外结核同时存在常见。
目的分析四川地區TB/HIV雙重感染者的特徵。方法迴顧性分析10年來本院收治的361例TB/HIV雙重感染者的臨床特徵及預後。結果住院艾滋病患者中TB/HIV雙重感染流行率為21.32%(361/1693),病死率為10.53%(38/361);其中78.67%(284/361)患者為肺結覈,73.96%(267/361)患者為肺外結覈,52.63%(190/361)患者為肺結覈及肺外結覈同時存在。臨床類型以肺外結覈為主(73.96%,267/361),繼髮性肺結覈次之(47.37%,171/361),再次為結覈性胸膜炎(23.55%,85/361),血型播散型肺結覈亦不少見,原髮性肺結覈少見;最常見的肺外結覈為淋巴結結覈、結覈性腦膜炎,其次是結覈性腹膜炎、心包結覈,尚存在骨結覈、腸結覈及盆腔結覈;兩箇部位同時感染最常見(75.35%,272/361);其次是單一部位感染(58.73%,212/361),3箇及以上部位感染亦較多見(16.90%,61/361);3箇及以上部位感染者病死率最高(18.03%,11/61),幾乎是單一部位及兩箇部位感染病死率的兩倍。結論四川地區住院艾滋病患者中TB/HIV雙重感染常見,結覈多部位感染、肺外結覈、肺結覈與肺外結覈同時存在常見。
목적분석사천지구TB/HIV쌍중감염자적특정。방법회고성분석10년래본원수치적361례TB/HIV쌍중감염자적림상특정급예후。결과주원애자병환자중TB/HIV쌍중감염류행솔위21.32%(361/1693),병사솔위10.53%(38/361);기중78.67%(284/361)환자위폐결핵,73.96%(267/361)환자위폐외결핵,52.63%(190/361)환자위폐결핵급폐외결핵동시존재。림상류형이폐외결핵위주(73.96%,267/361),계발성폐결핵차지(47.37%,171/361),재차위결핵성흉막염(23.55%,85/361),혈형파산형폐결핵역불소견,원발성폐결핵소견;최상견적폐외결핵위림파결결핵、결핵성뇌막염,기차시결핵성복막염、심포결핵,상존재골결핵、장결핵급분강결핵;량개부위동시감염최상견(75.35%,272/361);기차시단일부위감염(58.73%,212/361),3개급이상부위감염역교다견(16.90%,61/361);3개급이상부위감염자병사솔최고(18.03%,11/61),궤호시단일부위급량개부위감염병사솔적량배。결론사천지구주원애자병환자중TB/HIV쌍중감염상견,결핵다부위감염、폐외결핵、폐결핵여폐외결핵동시존재상견。
Objective To analyze clinical characteristics of patients with HIV and TB co-infection in Sichuan area. Methods Clinical manifestation and prognosis of 361 hospitalized cases with HIV and TB co-infection within resent ten years in Sichuan area were analyzed, retrospectively. Results The incidence of HIV and TB co-infection in hospitalized HIV/AIDS patients was 21.32%(361/1693) and the mortality was 10.53%(38/361). Among them, 78.67%(284/361) were with pulmonary tuberculosis, 73.96%(267/361) with extrapulmonary tuberculosis, 52.63%(190/361) with both pulmonary tuberculosis and extrapulmonary tuberculosis. The main tuberculosis clinical type was extrapulmonary tuberculosis (73.96%, 267/361), followed by secondary pulmonary tuberculosis (47.37%, 171/361) and tubercular pleuritis (23.55%, 85/361). Blood spreads pulmonary tuberculosis wasn’t rare, but primary pulmonary tuberculosis was rare. The main extrapulmonary tuberculosis was lymph node tuberculosis, followed by tubercular meningitis, tubercular peritonitis and pericardium tuberculosis. Bone tuberculosis, intestinal tuberculosis and the pelvic cavity tuberculosis also existed. The common infection was two spots infection (75.35%, 272/361), followed by one spot infection (58.73%, 212/361). Three and above spots infection was also common (16.90%, 61/361). The highest fatality rate was three and above spot infection group (18.03%, 11/61), nearly two times of that in one spot infection group and two spots infection group. Conclusions HIV and TB co-infection is common in hospitalized HIV/AIDS patient in Sichuan area. Multi-spots TB infection, extrapulmonary tuberculosis, both pulmonary tuberculosis and extrapulmonary tuberculosis co-existance are common.