CAJ | 학술논문

目的分别对儿童危重症患者血浆胶体渗透压、总渗透压与预后的关系进行研究，探讨与危重症患者预后的关系。方法回顾性分析2006年1月至2012年6月入住哈尔滨医科大学附属第一医院重症监护病房（ ICU）与儿科重症监护病房（ PICU）的187例患者，依据其入院时的血浆胶体渗透压与总渗透压的测定值分别进行分组，计算病死率，并且进行统计学比较。血浆胶体渗透压以20 mm Hg （即1.2 mOsm/kg H2 O）为界分为两组。总渗透压以260 mOsm/kg H2 O与283 mOsm/kg H2 O为界分为三组。结果低胶体渗透压患儿与正常胶体渗透压患儿相比，病死率高（62.3％vs．20.9％，P＜0.01）；而在总渗透压分析中，低总渗透压患儿与正常渗透压患儿相比，病死率无统计学差异（41.82％vs．27.35％，P＞0.05）。结论儿童危重症患者血浆胶体渗透压与患儿预后关系更为密切。
목적분별대인동위중증환자혈장효체삼투압、총삼투압여예후적관계진행연구，탐토여위중증환자예후적관계。방법회고성분석2006년1월지2012년6월입주합이빈의과대학부속제일의원중증감호병방（ ICU）여인과중증감호병방（ PICU）적187례환자，의거기입원시적혈장효체삼투압여총삼투압적측정치분별진행분조，계산병사솔，병차진행통계학비교。혈장효체삼투압이20 mm Hg （즉1.2 mOsm/kg H2 O）위계분위량조。총삼투압이260 mOsm/kg H2 O여283 mOsm/kg H2 O위계분위삼조。결과저효체삼투압환인여정상효체삼투압환인상비，병사솔고（62.3％vs．20.9％，P＜0.01）；이재총삼투압분석중，저총삼투압환인여정상삼투압환인상비，병사솔무통계학차이（41.82％vs．27.35％，P＞0.05）。결론인동위중증환자혈장효체삼투압여환인예후관계경위밀절。
Objective To investigate the relationship between the colloid osmotic pressure ( COP) as well as osmolality and the outcomes of critical children .Methods Totally 187 critical children were chosen from intensive care unit and PICU in the First Clinical College affiliated to Harbin Medical University from January 2006 to June 2012 ,and divided into different groups according to levels of COP and osmolalty .In groupⅠ, all children were divided into 2 subgroups based on COP ( the critical value was 20 mm Hg =1.2 mOsm/kg H2 O ) on the day of admission.In group program Ⅱ,the same children were divided into 3 subgroups on osmolality ( the critical value was in the range from 260 mOsm/kg H2 O and 283 mOsm/kg H2 O) which was measured on the day of admission .The mortality of patients was calculated .Chi-square test was used .Results Compared with children of normal colloid osmotic pressure group ,children of lower colloid osmotic pressure group had higher mortality (62.3%vs.20.9%,P<0.01 ) .Compared with children of normal osmalality group ,children of lower tatal osmotic pressure group did′t have significant difference ( 41.82% vs.27.35%, P >0.05 ) .Conclusions Compared with normal osmolality , normal colloid osmotic pressure had more closely relationship with the outcomes of critical children ,and it maybe a predictor of prognosis of the critical children .