CAJ | 학술논문

N-甲基-D-天冬氨酸（NMDA）受体是离子型兴奋性谷氨酸受体的一种亚型，生物体内已发现了3种NMDA受体亚基，且通过选择性剪接至少存在7种亚型，形成具有功能的多结合位点的大分子复合物。NMDA受体在中枢神经系统的突触传递、突触可塑性、学习记忆等生理过程中发挥着重要作用，且NMDA受体的异常会导致一些精神疾病及认知功能的障碍。
N-갑기-D-천동안산（NMDA）수체시리자형흥강성곡안산수체적일충아형，생물체내이발현료3충NMDA수체아기，차통과선택성전접지소존재7충아형，형성구유공능적다결합위점적대분자복합물。NMDA수체재중추신경계통적돌촉전체、돌촉가소성、학습기억등생리과정중발휘착중요작용，차NMDA수체적이상회도치일사정신질병급인지공능적장애。
N-methyl-D-aspartate(NMDA) receptor is a subtype of the ionic excitatory glutamate receptors. There are three kinds of NMDA receptor subunits and at least seven kinds of subtypes by alternative splicing, forming the macromolecular complexes with the functionality of multiple binding sites. NMDA receptor plays an im-portant role in the synaptic transmission, synaptic plasticity, learning memory and other physiological processes of central nervous system, and its abnormalities can cause mental illness and cognitive dysfunction.