CAJ | 학술논문

目的探讨剪切波超声弹性成像在深静脉血栓分期中的价值。方法95例患者共120条深静脉血栓患肢，根据临床症状起始时间分为急性组、亚急性组和慢性组，剪切波超声弹性成像测量血栓杨氏模量值，对比分析，并利用ROC曲线分析不同血栓分期间的杨氏模量值诊断截点。结果急性期、亚急性期、慢性期血栓杨氏模量平均值分别为（7.99±2.62）kPa、（13.52±2.31）kPa、（24.61±6.93）kPa，三者之间差异有统计学意义（ P＜0.05），血栓形成时间越长，杨氏模量值越大。以10.35 kPa作为诊断急性血栓的杨氏模量值截点时，敏感性86.67％，特异性97.44％；以17.05 kPa为诊断慢性血栓的杨氏模量值截点时，敏感性94.44％，特异性92.31％。结论杨氏模量值随血栓形成时间增加而增加，急性与亚急性血栓之间、亚急性与慢性血栓之间存在敏感性和特异性均较高的杨氏模量值诊断截点。
목적탐토전절파초성탄성성상재심정맥혈전분기중적개치。방법95례환자공120조심정맥혈전환지，근거림상증상기시시간분위급성조、아급성조화만성조，전절파초성탄성성상측량혈전양씨모량치，대비분석，병이용ROC곡선분석불동혈전분기간적양씨모량치진단절점。결과급성기、아급성기、만성기혈전양씨모량평균치분별위（7.99±2.62）kPa、（13.52±2.31）kPa、（24.61±6.93）kPa，삼자지간차이유통계학의의（ P＜0.05），혈전형성시간월장，양씨모량치월대。이10.35 kPa작위진단급성혈전적양씨모량치절점시，민감성86.67％，특이성97.44％；이17.05 kPa위진단만성혈전적양씨모량치절점시，민감성94.44％，특이성92.31％。결론양씨모량치수혈전형성시간증가이증가，급성여아급성혈전지간、아급성여만성혈전지간존재민감성화특이성균교고적양씨모량치진단절점。
Objective To discuss the value of ultrasound shear wave elastography imaging in the staging of deep vein thrombosis .Methods 120 extremities of 95 patients were enrolled in the present study .Based on the duration from occurrence of clinical symptoms , the thromboses were classified as acute , subacute and chronic .The elastic moduli were all measured and the diagnostic performance was assessed using ROC curves to get the cut -off values.Results The mean value of elastic moduli in acute ,subacute and chronic thrombosis was (7.99 ±2.62)kPa, (13.52 ±2.31)kPa,and (24.61 ±6.93)kPa respectively,with a significant difference among them(P<0.05).The longer the thrombus existed ,the greater the elastic modulus was .The cut off value was 10.35 kPa for acute thrombosis with a sensitivity of 86.67 and a specificity of 97.44 and 17.05 kPa for chronic thrombosis with a sensitivity of 94.44 and a specificity of 92.31 .Conclusions The modulus of elasticity increases with the duration of thrombosis .There are cut-off values between acute thrombosis and subacute thrombosis and between subacute thrombosis and chronic thrombosis,of which the sensitivity and specificity are both high .