CAJ | 학술논문

目的比较注射与口服青霉素类药物不良反应的差别。方法采用回顾性分析方法对2007～2012年江苏省不良反应中心收集到的青霉素类药品的不良反应报告进行分析。结果江苏省注射用青霉素的不良反应数为6082例，占92．98％；口服青霉素的不良反应数为454例，占6．94％。注射用青霉素有新的严重的不良反应2例。注射用青霉素不良反应病例经治疗后有9例死亡病例，3例病人留下后遗症；口服青霉素的不良反应经治疗后均痊愈或好转。结论口服青霉素类药物不良反应数量少，且严重程度低，经治疗后无死亡或留下后遗症的病例。
목적비교주사여구복청매소류약물불량반응적차별。방법채용회고성분석방법대2007～2012년강소성불량반응중심수집도적청매소류약품적불량반응보고진행분석。결과강소성주사용청매소적불량반응수위6082례，점92．98％；구복청매소적불량반응수위454례，점6．94％。주사용청매소유신적엄중적불량반응2례。주사용청매소불량반응병례경치료후유9례사망병례，3례병인류하후유증；구복청매소적불량반응경치료후균전유혹호전。결론구복청매소류약물불량반응수량소，차엄중정도저，경치료후무사망혹류하후유증적병례。
Objective Compare with injection penicillin drugs and oral penicillin drugs for ADR .Method The adverse reaction re-ports of penicillin drugs collected by Jiangsu adverse reaction center from 2007 to 2012 were analyzed retrospectively .Result The case number of adverse reactions of injection penicillin was 6 082 ,accounting for 92 .98% ;Oral penicillin adverse reactions num-ber was 454 cases ,accounting for 6 .94% ;The injection penicillin drugs had new serious adverse reactions in 2 cases ;After the treatment of injection penicillin adverse reaction ,9 cases were die and 3 cases left sequela ;On the other hand ,the cases of oral penicillin adverse reactions were recoveried or better after treatment .Conclusion For the adverse drug reactions of oral penicillin , the quantity was less and the serious degree was low and no death or sequela was reported after treatment .