CAJ | 학술논문

目的建立养心开郁片质量控制标准。方法采用薄层色谱法对处方中红参、黄芪进行定性鉴别；采用高效液相色谱-蒸发光散射器（HPLC-ELSD）法测定养心开郁片中黄芪甲苷的含量。结果样品中红参和黄芪定性鉴别薄层色谱特征明显，专属性强；有效成分黄芪甲苷进样量在2．048～20．48μg范围内呈良好线性关系，r＝0．9997。平均加样回收率为99．2％，RSD为1．3％（n＝9）。结论建立的分析方法简便可行、准确、专属性强，可作为养心开郁片的质量控制方法。
목적건립양심개욱편질량공제표준。방법채용박층색보법대처방중홍삼、황기진행정성감별；채용고효액상색보-증발광산사기（HPLC-ELSD）법측정양심개욱편중황기갑감적함량。결과양품중홍삼화황기정성감별박층색보특정명현，전속성강；유효성분황기갑감진양량재2．048～20．48μg범위내정량호선성관계，r＝0．9997。평균가양회수솔위99．2％，RSD위1．3％（n＝9）。결론건립적분석방법간편가행、준학、전속성강，가작위양심개욱편적질량공제방법。
Objective To establish a quality control method forYangxinkaiyu Tablets .Methods Ginseng and Astragalus in the pre-scription were identified by TLC .Quantitative analysis of astragaloside A which is an effective component of the formula was adopted by HPLC-ELSD .Results TLC were clear without any interference .The linear range was 2 .048-20 .48 μg (r=0 .999 7) for astragaloside A .The average recovery rate was 99 .2% with RSD 1 .3% (n=9) .Conclusion The method was easy ,accurate , realizable and reproducible ,and could be used for the quality control of Yangxinkaiyu Tablets .