CAJ | 학술논문

目的：探讨头体针结合治疗急性期脑梗塞患者对血清中血管内皮生长因子（ VEGF）的影响及其作用机理。方法：将87例急性期脑梗塞患者随机分为治疗组45例及对照组42例，治疗组采用西药联合头体针治疗，对照组单纯用西药治疗，采用酶联免疫吸附双抗体夹心法（ ELISA ）对两组患者治疗前后血清VEGF含量进行测定。结果：两组治疗后第7天和第14天血清VEGF含量都高于治疗前，差异均有显著性意义（ P＜0．01、P＜0．05），其中第7天血清VEGF含量达到较高水平，且治疗组治疗后的第7天和第14天的血清VEGF含量较对照组高，差异有显著性意义（ P＜0．01）。结论：头体针治疗可明显提高临床疗效与其维持血清VEGF含量相对较高的水平有关。
목적：탐토두체침결합치료급성기뇌경새환자대혈청중혈관내피생장인자（ VEGF）적영향급기작용궤리。방법：장87례급성기뇌경새환자수궤분위치료조45례급대조조42례，치료조채용서약연합두체침치료，대조조단순용서약치료，채용매련면역흡부쌍항체협심법（ ELISA ）대량조환자치료전후혈청VEGF함량진행측정。결과：량조치료후제7천화제14천혈청VEGF함량도고우치료전，차이균유현저성의의（ P＜0．01、P＜0．05），기중제7천혈청VEGF함량체도교고수평，차치료조치료후적제7천화제14천적혈청VEGF함량교대조조고，차이유현저성의의（ P＜0．01）。결론：두체침치료가명현제고림상료효여기유지혈청VEGF함량상대교고적수평유관。
Objective:To investigate the effects of serum vascular endothelial growth factor ( VEGF) on the pa-tients of acute cerebral infarction by scalp with body acupuncture and the mechanism of treatment .Methods:87 cases of cerebral infarction at acute stage were randomly divided into treatment group ( 45 cases ) and control group ( 42 cases ) .The treatment group was treated by scalp with body acupuncture combined with western medicine;the control group was simply treated by western medicine .Before and after treatment the content of serum VEGF was determined by ELISA in the two groups .Results:The contents of VEGF at the 7th,14th day after treatment in the two groups were significantly increased than those before treatment , the differences were significant (P<0.01,P<0.05), the contents of VEGF at the 7th day after treatment reached a higher level , the contents of VEGF in the treatment group at the 7th,14th day after treatment were significantly increased than those in the control group , the differences were significant ( P<0 .01 ) .Conclusion:Clinical efficacy is related to the increase of the content of serum VEGF by scalp with body acupuncture .