中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2013年
7期
2856-2858
,共3页
王宁%常丽丽%张静%马天%张淑梅%张军霞%封永芳%张学丛
王寧%常麗麗%張靜%馬天%張淑梅%張軍霞%封永芳%張學叢
왕저%상려려%장정%마천%장숙매%장군하%봉영방%장학총
肝炎%自主神经系统%心率变异%胃排空
肝炎%自主神經繫統%心率變異%胃排空
간염%자주신경계통%심솔변이%위배공
Hepatitis%Autonomic nervous system%Heart rate variability%Gastic emptying
目的观察急性肝炎患者自主神经功能的变化,探讨急性肝炎患者胃动力异常的病理机制。方法石家庄市第一医院消化内一科2010年10月至2011年9月就诊的急性肝炎患者70例,其中男40例,女30例。健康志愿者35名,男20名,女15名。采用24 h动态心电图,记录24 h、早餐前后各1 h的动态心电图检测结果,进行心率变异分析,测定自主神经功能。结果急性肝炎组24 h总体自主神经功能活动异常,表现为交感神经活跃,SDNNindex(60.07±13.54 vs.77.82±19.74),ULF(269785.9±19774.27 vs.316798.1±33428.03)差异有统计学意义(P<0.05);迷走神经功能减弱,RMSSD(38.92±12.25 vs.24.63±8.46),HF(329951.9±189775.89 vs.261198.79±116361.79)差异有统计学意义(P<0.05);交感迷走平衡失调(0.96±0.53 vs.2.01±0.83),差异有统计学意义(P<0.05);餐前与餐后自主神经活动异常,表现为交感神经功能亢进,SDNNindex为77.29±20.54 vs.205.92±78.66,迷走神经功能减弱,RMSSD为34.59±11.29 vs.31.09±9.87。结论急性肝炎患者存在自主神经功能异常,可能与急性肝炎患者胃动力障碍有关。
目的觀察急性肝炎患者自主神經功能的變化,探討急性肝炎患者胃動力異常的病理機製。方法石傢莊市第一醫院消化內一科2010年10月至2011年9月就診的急性肝炎患者70例,其中男40例,女30例。健康誌願者35名,男20名,女15名。採用24 h動態心電圖,記錄24 h、早餐前後各1 h的動態心電圖檢測結果,進行心率變異分析,測定自主神經功能。結果急性肝炎組24 h總體自主神經功能活動異常,錶現為交感神經活躍,SDNNindex(60.07±13.54 vs.77.82±19.74),ULF(269785.9±19774.27 vs.316798.1±33428.03)差異有統計學意義(P<0.05);迷走神經功能減弱,RMSSD(38.92±12.25 vs.24.63±8.46),HF(329951.9±189775.89 vs.261198.79±116361.79)差異有統計學意義(P<0.05);交感迷走平衡失調(0.96±0.53 vs.2.01±0.83),差異有統計學意義(P<0.05);餐前與餐後自主神經活動異常,錶現為交感神經功能亢進,SDNNindex為77.29±20.54 vs.205.92±78.66,迷走神經功能減弱,RMSSD為34.59±11.29 vs.31.09±9.87。結論急性肝炎患者存在自主神經功能異常,可能與急性肝炎患者胃動力障礙有關。
목적관찰급성간염환자자주신경공능적변화,탐토급성간염환자위동력이상적병리궤제。방법석가장시제일의원소화내일과2010년10월지2011년9월취진적급성간염환자70례,기중남40례,녀30례。건강지원자35명,남20명,녀15명。채용24 h동태심전도,기록24 h、조찬전후각1 h적동태심전도검측결과,진행심솔변이분석,측정자주신경공능。결과급성간염조24 h총체자주신경공능활동이상,표현위교감신경활약,SDNNindex(60.07±13.54 vs.77.82±19.74),ULF(269785.9±19774.27 vs.316798.1±33428.03)차이유통계학의의(P<0.05);미주신경공능감약,RMSSD(38.92±12.25 vs.24.63±8.46),HF(329951.9±189775.89 vs.261198.79±116361.79)차이유통계학의의(P<0.05);교감미주평형실조(0.96±0.53 vs.2.01±0.83),차이유통계학의의(P<0.05);찬전여찬후자주신경활동이상,표현위교감신경공능항진,SDNNindex위77.29±20.54 vs.205.92±78.66,미주신경공능감약,RMSSD위34.59±11.29 vs.31.09±9.87。결론급성간염환자존재자주신경공능이상,가능여급성간염환자위동력장애유관。
Objective To observe the changes of autonomic function in patients with acute hepatitis ,and to investigate pathological mechanism of the abnormal gastric motility .Methods Acute hepatitis patients were 70 cases,from Shi Jia Zhuang No 1 Hospital Department of Digestive 1,from October 2010 to September 2011,include 40 males and 30 females.Healthy cases 35,include 20 males and 15 females.The autonomic function was recorded with Holter for 24 h.HRV ( Heart rate variability ) of 24 h and 1 h before and after breakfast were analyzed . Results Autonomic nerve function of 24 h and before and after meal was abnormal .SDNNindex(60.07 ±13.54 vs. 77.82 ±19.74 ) and ULF ( 269 785.9 ±19 774.27 vs.316 798.1 ±33 428.03 ) increased ( P <0.05 );RMSSD (38.92 ±12.25 vs.24.63 ±8.46)and HF(329 951.9 ±189 775.89 vs.261 198.79 ±116 361.79 ) decreased(P<0.05);LF/HF(0.96 ±0.53 vs.2.01 ±0.83)dysequilibrium(P<0.05);Autonomic nerve function of before and after meal was abnormal.SDNNindex (77.29 ±20.54 vs.205.92 ±78.66)increased,RMSSD(34.59 ±11.29 vs. 31.09 ±9.87 ) decreased.Conclusions Autonomic function were abnormal in patients with acute hapatitis ,which maybe relation with gastric motility disorder .