CAJ | 학술논문

目的探讨早期气管插管对重症结核性脑膜炎患者预后的影响。方法将我院2009年1月至2012年12月收治的Glasgow评分3～8分的80例重症结核性脑膜炎患者，根据入ICU后气管插管时间不同分为早期气管插管组和常规气管插管组，比较两组的氧合指数、机械通气时间及ICU住院时间，按照GOS评分判定患者6个月的生存质量。结果早期气管插管组氧合指数维持相对较高水平（P＜0.01），机械通气时间明显缩短（P＜0.05），常规气管插管组病死率和致残率均增加（P＜0.05）。结论早期气管插管可以改善组织氧供，减少低氧血症，避免或减少吸入性肺炎发生，缩短机械通气及ICU住院时间，降低病死率和致残率，有利于重症结核性脑膜炎患者的预后。
목적탐토조기기관삽관대중증결핵성뇌막염환자예후적영향。방법장아원2009년1월지2012년12월수치적Glasgow평분3～8분적80례중증결핵성뇌막염환자，근거입ICU후기관삽관시간불동분위조기기관삽관조화상규기관삽관조，비교량조적양합지수、궤계통기시간급ICU주원시간，안조GOS평분판정환자6개월적생존질량。결과조기기관삽관조양합지수유지상대교고수평（P＜0.01），궤계통기시간명현축단（P＜0.05），상규기관삽관조병사솔화치잔솔균증가（P＜0.05）。결론조기기관삽관가이개선조직양공，감소저양혈증，피면혹감소흡입성폐염발생，축단궤계통기급ICU주원시간，강저병사솔화치잔솔，유리우중증결핵성뇌막염환자적예후。
Objective To explore the influence of early intubation on severe tuberculous meningitis patients′outcome.Methods 80 cases of severe tuberculous meningitis with GCS score 3-8 points were divided into the early intubation group and the regular intubation group according to the different time of tracheal intubation , comparing PaO2/FiO2 ,mechanical ventilation time and ICU length of stay , the quality of life of the patients six months in according to the GOS score of two groups .Results PaO2/FiO2 of the early intubation group were higher than regular intubation group , mechanical ventilation time and ICU length of stay was significantly shorter , the mortality and morbidity of the regular intubation group increased .Conclusions The early tracheal intubation can improve tissue oxygenation,reduce hypoxemia,avoid or reduce aspiration pneumonia ,shorter mechanical ventilation time and reduce complications , lower mortality and morbidity , improve prognosis rate obviously to the severe tuberculous meningitis patients .