CAJ | 학술논문

目的：观察竹沥胶囊治疗急性咽喉炎的临床疗效及不良反应。方法：将符合急性咽喉炎诊断标准的80例患者按照就诊次序随机分为竹沥胶囊组和鲜竹沥口服液组,每组40例。两组分别在常规治疗基础上加服竹沥胶囊(0.1mg/次,tid)和鲜竹沥口服液(30ml/次,tid),每日密切观察患者体温、咽痛、咽部红肿以及咳嗽、咯痰等临床症状变化。结果：两组患者服用药物后体温均下降,其中竹沥胶囊组患者治疗后体温下降更为明显,治疗前后比较具有统计学差异(P=0.011),且与对照组比较也具有统计学差异(P=0.023)。竹沥胶囊组患者服用后咽痛、咳嗽、咯痰等症状明显改善,改善时间较鲜竹沥口服液组缩短1天,两组比较差异具有统计学意义(P=0.0011,P=0.0085,P=0.010)。竹沥胶囊组咽痛,咽部红肿、咳嗽、咯痰等症状也明显改善,其总有效率为97.5%；鲜竹沥口服液组总有效率80.0%。两组比较差异具有统计学意义(χ2=6.13,P=0.013)。两组均未见明显的不良反应。结论：竹沥胶囊治疗急性咽喉炎在改善咽部症状方面优于鲜竹沥口服液。
목적：관찰죽력효낭치료급성인후염적림상료효급불량반응。방법：장부합급성인후염진단표준적80례환자안조취진차서수궤분위죽력효낭조화선죽력구복액조,매조40례。량조분별재상규치료기출상가복죽력효낭(0.1mg/차,tid)화선죽력구복액(30ml/차,tid),매일밀절관찰환자체온、인통、인부홍종이급해수、각담등림상증상변화。결과：량조환자복용약물후체온균하강,기중죽력효낭조환자치료후체온하강경위명현,치료전후비교구유통계학차이(P=0.011),차여대조조비교야구유통계학차이(P=0.023)。죽력효낭조환자복용후인통、해수、각담등증상명현개선,개선시간교선죽력구복액조축단1천,량조비교차이구유통계학의의(P=0.0011,P=0.0085,P=0.010)。죽력효낭조인통,인부홍종、해수、각담등증상야명현개선,기총유효솔위97.5%；선죽력구복액조총유효솔80.0%。량조비교차이구유통계학의의(χ2=6.13,P=0.013)。량조균미견명현적불량반응。결론：죽력효낭치료급성인후염재개선인부증상방면우우선죽력구복액。
Objective:Observe the clinical efficacy and adverse reactions of Zhuli capsules to treat acute pharyngitis.Methods:80 patients meeting the diagnostic criteria of acute pharyngitis were randomly divided into the Zhuli capsules group and Xianzhuli oral group,40 cases in each.On the basis of conventional therapy,one group was served Zhuli capsules (0.1mg/time,tid) and another group served Xianzhuli oral solution (30ml/tid).Observe the patients' clinical symptoms changes in body temperature,sore throat,throat irritation,cough and expectoration.Results:Patients' body temperature dropped after taking drugs,and the temperature of patients in Zhuli capsules decreased more significantly.There is significant difference (P=0.011) before and after treatment,and compared with the control group also exist statistical difference (P=0.023).The sore throat,cough,cough up phlegm and other symptoms of patients in Zhuli capsules were improved significantly after taking drugs,and the improving time was shorten 1 day than that in Xianzhuli oral group.The difference between the two groups was statistically significant (P=0.0011,P=0.0085,P=0.010).The sore throat,throat irritation,cough,expectoration and other symptoms were significantly improved in Zhuli capsules group,and the total effective rate was 97.5%.The total effective rate of Xianzhui oral group was 80.0%.The difference between the two groups is statistically significant (χ2=6.13,P=0.013).And the two groups showed no significant adverse reactions.Conclusion:In the treatment of acute sore throat and in the aspect of improving pharyngeal symptoms,Zhuli capsules is better than that of Xianzhuli oral.