CAJ | 학술논문

目的：研究探讨化疗对乳腺癌患者血清总胆固醇及甘油三酯水平的影响及临床意义。方法：对我院128例乳腺癌患者化疗前后的血清总胆固醇及甘油三酯变化和相关因素进行分析，同时收集100例健康体检者作为对照组分析。结果：血清总胆固醇检测量与对照组相比偏低，甘油三脂无明显差异。随着化疗时间的增加，患者的血清总胆固醇升高较为明显，与化疗前相比有明显差异；甘油三脂水平化疗前后无明显差异，不具有统计学意义。另外各种化疗方案对血清总胆固醇和甘油三脂的影响无差异。结论：乳腺癌患者血清总胆固醇相对较低，随着化疗时间增长患者的血清总胆固醇也逐步升高，而对患者的甘油三脂水平影响不明显。
목적：연구탐토화료대유선암환자혈청총담고순급감유삼지수평적영향급림상의의。방법：대아원128례유선암환자화료전후적혈청총담고순급감유삼지변화화상관인소진행분석，동시수집100례건강체검자작위대조조분석。결과：혈청총담고순검측량여대조조상비편저，감유삼지무명현차이。수착화료시간적증가，환자적혈청총담고순승고교위명현，여화료전상비유명현차이；감유삼지수평화료전후무명현차이，불구유통계학의의。령외각충화료방안대혈청총담고순화감유삼지적영향무차이。결론：유선암환자혈청총담고순상대교저，수착화료시간증장환자적혈청총담고순야축보승고，이대환자적감유삼지수평영향불명현。
Objective: To study and investigate the influence of chemotherapy on the level of total serum cholesterol and triglycerides of breast cancer patients and its clinical significance. Methods:The changes of total serum cholesterol and triglycerides of 128 breast cancer patients before and after chemotherapy and its related factors were analyzed, and at the same time collected 100 cases of healthy physical examination as control group. Results: Compared with control group, the total serum cholesterol was lower, and triglycerides were no obvious different. With the chemotherapy time increased, the total serum cholesterol in patients rose obviously, there is significant difference with that before treatment;And there were no significant difference of triglycerides level before and after chemotherapy. Various chemotherapy regimens didn’t affect the level of total serum cholesterol and triglycerides. Conclusion:The level of total serum cholesterol and triglycerides of breast cancer patients are low relatively, as chemotherapy time goes on, the total serum cholesterol in patients rise gradually, and there are no obvious changes of triglycerides.