CAJ | 학술논문

目的：探讨血浆D-D及高敏C反应蛋白（ hs-CRP）在妊娠高血压综合征患者血清中的检测及意义。方法：选择2011年9月～2012年9月在我院住院妊高征患者50例，其中子痫前期15例，轻度子痫22例，重度子痫13例，同期妊娠晚期健康妇女30例作为对照组。以免疫比浊法检测血浆D-D及hs-CRP水平。结果：实验组血浆D-D、CRP水平均高于对照组（ P＜0．01），轻度子痫、重度子痫患者血浆D-D及hs-CRP水平高于子痫前期患者（P＜0．05），重度子痫高于轻度子痫患者（P＜0．05）。 CRP与D-D水平呈正相关，r＝0．61，P＜0．01。结论：D-D、CRP均参与了妊娠高血压综合征的发病进程，二者在妊娠高血压综合征患者中明显升高，并与疾病严重程度呈正相关。
목적：탐토혈장D-D급고민C반응단백（ hs-CRP）재임신고혈압종합정환자혈청중적검측급의의。방법：선택2011년9월～2012년9월재아원주원임고정환자50례，기중자간전기15례，경도자간22례，중도자간13례，동기임신만기건강부녀30례작위대조조。이면역비탁법검측혈장D-D급hs-CRP수평。결과：실험조혈장D-D、CRP수평균고우대조조（ P＜0．01），경도자간、중도자간환자혈장D-D급hs-CRP수평고우자간전기환자（P＜0．05），중도자간고우경도자간환자（P＜0．05）。 CRP여D-D수평정정상관，r＝0．61，P＜0．01。결론：D-D、CRP균삼여료임신고혈압종합정적발병진정，이자재임신고혈압종합정환자중명현승고，병여질병엄중정도정정상관。
Objective:To investigate the plasma levels of D -D and high sensitive C reactive protein ( hs-CRP) in the detection and sig-nificance of serum in patients with pregnancy -induced hypertension syndrome .Methods:From 2011 September ~2012 year in Septem-ber in our hospital 50 patients with PIH,15 cases with mild preeclampsia ,eclampsia in 22 cases,13 cases of severe preeclampsia during late pregnancy ,30 healthy women as control group .In the detection of plasma D -D and hs-immunoglobulin CRP level the turbidimetric method.Results:In the experimental group,plasma D-D,CRP levels were higher than those in the control group (P<0.01),mild pre-eclampsia,severe preeclampsia patients plasma levels of D -D and hs-CRP levels were higher in patients with preeclampsia ,severe pre-eclampsia (P<0.05) is higher than that of patients with mild preeclampsia (P<0.05).CRP was positively correlated with the level of D-D,r=0.61,P<0.01.Conclusion:D-D,CRP were involved in the pathogenesis of pregnancy induced hypertension syndrome ,two in the syndrome in patients with pregnancy induced hypertension and increased significantly ,and the disease severity was positively correlated with.