CAJ | 학술논문

目的：观察臭氧关节腔内注射治疗老年退行性膝骨性关节炎的临床疗效。方法：门诊收治老年性骨性膝关节炎患者120例，随机分为A、B、C 3组。 A组单纯应用混合消炎镇痛液（曲安奈德、利多卡因和生理盐水混合液10ml）；B组患者首先应用0．25％利多卡因5ml进行局部麻醉，之后给予臭氧25ug浓度共20ml；C组患者联合2种治疗方法，3组均治疗5周。 A、B、C 3组经治疗后分别观察1周后、5周后、12周后患者的疼痛评分缓解情况。结果：A、B、C 3组经治疗后疼痛评分均有缓解，治疗前后疼痛评分统计学分析有差异；经治疗后第1周和第5周以及第12周的疼痛评分组间比较具有统计学差异，其中A、B组未见统计学差异，B、C，A、C组间第1周第5周及第12周的疼痛评分对照均具有统计学差异。各组患者的膝关节功能均得到改善。结论：臭氧对关节腔内注射治疗老年退行性膝骨性关节炎有显著疗效，联合小剂量皮质类固醇应用效果更佳。
목적：관찰취양관절강내주사치료노년퇴행성슬골성관절염적림상료효。방법：문진수치노년성골성슬관절염환자120례，수궤분위A、B、C 3조。 A조단순응용혼합소염진통액（곡안내덕、리다잡인화생리염수혼합액10ml）；B조환자수선응용0．25％리다잡인5ml진행국부마취，지후급여취양25ug농도공20ml；C조환자연합2충치료방법，3조균치료5주。 A、B、C 3조경치료후분별관찰1주후、5주후、12주후환자적동통평분완해정황。결과：A、B、C 3조경치료후동통평분균유완해，치료전후동통평분통계학분석유차이；경치료후제1주화제5주이급제12주적동통평분조간비교구유통계학차이，기중A、B조미견통계학차이，B、C，A、C조간제1주제5주급제12주적동통평분대조균구유통계학차이。각조환자적슬관절공능균득도개선。결론：취양대관절강내주사치료노년퇴행성슬골성관절염유현저료효，연합소제량피질류고순응용효과경가。
Objective:To observe the clinical effect of osteoarthritis of Knee by ozone intraarticular injection .Methods:120 cases came to our clinic service dignosised regressive osteoarthritis of Knee ,were divided into ABC three groups randomly .Group A was given intraarticular injection by mixed analgesia fluid (triamcinolone acetonide 8mg+lidocaine 0.25%+physiological saline 10ml);group B, given lidocaine 0.25%5ml for local anesthesia firstly ,was intraarticular injected by ozone 25ug 20ml;group C combined A with B .All cases have continued treatment for five weeks .Pain relieved scores were recorded in the first week ,the fifth week and the twelfth week . Results:All cases had pain relieved after treatment .There were significant statistic difference between pretherapy and post -treatment a-mong three groups in the first week ,the fifth week and the twelfth week ,and there was no statistic difference between A and B .Significant statistic difference between B and C ,A and C had been found in all three different times .Joint function improved happened to all cases . Conclusion:Regressive osteoarthritis of knee will have significant effection by ozone intraarticular injection ,there would be well by combi-ning corticosteroids by small dose .