CAJ | 학술논문

肾脏是药物排泄的主要途径，肾功能不全患者可使药物的排泄减慢，造成药物的半衰期延长，增加药物的毒性。因此对肾功能不全患者进行药物治疗时，应注意剂量和品种的选择，并应注意避免同时使用对肾脏有毒性的药物。
신장시약물배설적주요도경，신공능불전환자가사약물적배설감만，조성약물적반쇠기연장，증가약물적독성。인차대신공능불전환자진행약물치료시，응주의제량화품충적선택，병응주의피면동시사용대신장유독성적약물。
the kidney is the main way of drug excretion, renal insufficiency patients can make drug excretion slowed down, causing drug half-life is prolonged, increased drug toxicity. So for renal insufficiency patients for drug treatment, attention should be paid to the dose and the choice of varieties, and should pay attention to avoid drug use is toxic to the kidney.