中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2013年
9期
3935-3938
,共4页
李佳%胡兵%胡滨%陈磊%朱家安%衣晓蕾%陈捷
李佳%鬍兵%鬍濱%陳磊%硃傢安%衣曉蕾%陳捷
리가%호병%호빈%진뢰%주가안%의효뢰%진첩
超声检查%导管消融术%前列腺%超声造影
超聲檢查%導管消融術%前列腺%超聲造影
초성검사%도관소융술%전렬선%초성조영
Ultrasonography%Catheter ablation%Prostate%Contrast-enhanced ultrasonography
目的探讨超声造影动态观察正常实验犬前列腺射频消融灶范围及消融灶演变的可行性。方法10条雄性实验犬随机分为消融术后一周组和一个月组，每组5条。对每条犬的前列腺一侧叶行射频消融。射频术后一个月组犬，在处死前对另一侧叶行射频消融，该侧消融灶作为射频消融即刻组。定期对实验犬行经直肠常规超声、超声造影检查，同时采用超声造影测量消融灶体积。观察超声造影对前列腺消融灶的评价效果，并与最终的大体病理测量结果比较。结果射频消融后即刻、一周和一个月超声造影评价消融灶体积分别为（0.77±0.34） cm3、（1.11±0.61） cm3和（0.19±0.09） cm3。相应时期病理测量体积分别为（0.85±0.28）cm3、（0.96±0.31）cm3和（0.20±0.06）cm3。超声造影在各个时期均能准确评价消融灶的范围，其测量结果与病理结果比较无统计学差异（P＞0.05），同时超声造影能准确反映消融灶及周边组织的血流分布情况。结论超声造影能反映前列腺射频消融灶的范围并能动态显示消融灶血流灌注的变化。
目的探討超聲造影動態觀察正常實驗犬前列腺射頻消融竈範圍及消融竈縯變的可行性。方法10條雄性實驗犬隨機分為消融術後一週組和一箇月組，每組5條。對每條犬的前列腺一側葉行射頻消融。射頻術後一箇月組犬，在處死前對另一側葉行射頻消融，該側消融竈作為射頻消融即刻組。定期對實驗犬行經直腸常規超聲、超聲造影檢查，同時採用超聲造影測量消融竈體積。觀察超聲造影對前列腺消融竈的評價效果，併與最終的大體病理測量結果比較。結果射頻消融後即刻、一週和一箇月超聲造影評價消融竈體積分彆為（0.77±0.34） cm3、（1.11±0.61） cm3和（0.19±0.09） cm3。相應時期病理測量體積分彆為（0.85±0.28）cm3、（0.96±0.31）cm3和（0.20±0.06）cm3。超聲造影在各箇時期均能準確評價消融竈的範圍，其測量結果與病理結果比較無統計學差異（P＞0.05），同時超聲造影能準確反映消融竈及週邊組織的血流分佈情況。結論超聲造影能反映前列腺射頻消融竈的範圍併能動態顯示消融竈血流灌註的變化。
목적탐토초성조영동태관찰정상실험견전렬선사빈소융조범위급소융조연변적가행성。방법10조웅성실험견수궤분위소융술후일주조화일개월조，매조5조。대매조견적전렬선일측협행사빈소융。사빈술후일개월조견，재처사전대령일측협행사빈소융，해측소융조작위사빈소융즉각조。정기대실험견행경직장상규초성、초성조영검사，동시채용초성조영측량소융조체적。관찰초성조영대전렬선소융조적평개효과，병여최종적대체병리측량결과비교。결과사빈소융후즉각、일주화일개월초성조영평개소융조체적분별위（0.77±0.34） cm3、（1.11±0.61） cm3화（0.19±0.09） cm3。상응시기병리측량체적분별위（0.85±0.28）cm3、（0.96±0.31）cm3화（0.20±0.06）cm3。초성조영재각개시기균능준학평개소융조적범위，기측량결과여병리결과비교무통계학차이（P＞0.05），동시초성조영능준학반영소융조급주변조직적혈류분포정황。결론초성조영능반영전렬선사빈소융조적범위병능동태현시소융조혈류관주적변화。
Objective To evaluate the lesions produced by radiofrequency ablation ( RFA) in a canine model with contrast-enhanced ultrasonography (CEUS)and investigate the feasibility to predict these lesions .Methods 10 male dogs underwent RFA of the prostate .RF was delivered under transrectal ultrasound ( TRUS ) guidance .The examinations of CEUS were performed immediately , 1 week and 1 month after RF procedure .Subsequently , all animals were sacrificed and the prostates were gotten for pathologic analysis .Results The RFA lesions volume measured by CEUS in different periods were ( 0.77 ±0.34 ) cm3 , ( 1.11 ±0.61 ) cm3 and ( 0.19 ±0.09 ) cm3 , respectively .The lesions size observed on pathological were ( 0.85 ±0.28 ) cm3 , ( 0.96 ±0.31 ) cm3 and ( 0.20 ± 0.06 ) cm3 .CEUS was able to monitor the lesions in real time .After RFA we measured the lesion′s volume with CEUS.There were no significant differences with the pathologic results .Ultrasound imaging of the ablation areas at different time had its own characteristics , which was caused by pathological transformation .Conclusion CEUS appears to be an accurate modality for assess of RFA lesions .
