CAJ | 학술논문

目的探讨依托咪酯与丙泊酚用于全身麻醉维持对患者血流动力学的影响。方法选择ASAⅠ～Ⅱ级择期手术全身麻醉的患者80例，随机分为2组，每组40例。诱导均为舒芬太尼0.3ug/kg静脉推注，治疗组给予依托咪酯0.3mg/kg静脉推注，瑞芬太尼0.1~0.3ug/（kg·min）加依托咪酯0.6~1.2mg/(kg·h)维持；对照组给予丙泊酚2.0mg/kg静脉推注，瑞芬太尼0.1~0.3ug/（kg·min）加丙泊酚6~10mg/（kg·min）维持。结果2组患者术中血流动力学均较稳定，但治疗组的波动明显低于对照组（P<0.05）。治疗组4例(10%)出现注射痛，明显小于对照组16例(40%，P<0.05)。结论依托咪酯对血流动力学的影响优于丙泊酚，更适合全身麻醉维持。
목적탐토의탁미지여병박분용우전신마취유지대환자혈류동역학적영향。방법선택ASAⅠ～Ⅱ급택기수술전신마취적환자80례，수궤분위2조，매조40례。유도균위서분태니0.3ug/kg정맥추주，치료조급여의탁미지0.3mg/kg정맥추주，서분태니0.1~0.3ug/（kg·min）가의탁미지0.6~1.2mg/(kg·h)유지；대조조급여병박분2.0mg/kg정맥추주，서분태니0.1~0.3ug/（kg·min）가병박분6~10mg/（kg·min）유지。결과2조환자술중혈류동역학균교은정，단치료조적파동명현저우대조조（P<0.05）。치료조4례(10%)출현주사통，명현소우대조조16례(40%，P<0.05)。결론의탁미지대혈류동역학적영향우우병박분，경괄합전신마취유지。
Objective To investigate relying etomidate and propofol for general anesthesia induced impact on hemodynamics in patients with clinical ef icacy.Methods ASAⅠ~Ⅱ grade elective general anesthesia, 80 patients under the randomized into the treatment group and the control group, 40 cases in each.Treatment the group given remifentanil 0.1-0.3ug/kg.min plus etomidate 0.6-1.2mg/kg.h maintain.The control group was given the Swiss of remifentanil 0.1-0.3ug/kg.min plus propofol 6-10mg/kg. h maintain.Results 2 groups of patients were stable, but the fluctuatio-ns of the treatment group was significantly lower than the control group (P<0.05).Treatment group and 4 patients (10%) of pain in the control group had 16 cases (40%,P<0.05)Conclusion etomidate on cardiovasc ular responses to propofol,more suitable for general anesthesia maintain ed.