医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2013年
9期
90-91
,共2页
王宏志%何仁胜%方春华%胡亚华%刘俊
王宏誌%何仁勝%方春華%鬍亞華%劉俊
왕굉지%하인성%방춘화%호아화%류준
腹泻型肠易激综合征%复方谷氨酰胺肠溶胶囊%酪酸梭菌%临床疗效
腹瀉型腸易激綜閤徵%複方穀氨酰胺腸溶膠囊%酪痠梭菌%臨床療效
복사형장역격종합정%복방곡안선알장용효낭%락산사균%림상료효
Diarrhea type irritable bowel syndrome%Compound glutamine enteric capsules%Clostridium butyricum%Clinical curative ef ect
目的观察复方谷氨酰胺肠溶胶囊联合酪酸梭菌治疗腹泻型肠易激综合征（IBS-D）的临床疗效。方法120例IBS-D患者，随机分为观察组60例，予复方谷氨酰胺肠溶胶囊联合酪酸梭菌治疗；对照组60例，予复方谷氨酰胺肠溶胶囊治疗，两组均以4w为一疗程。结果观察组总有效率90.0%，对照组总有效率63.3%。观察组疗效高于对照组(P<0．05)；观察组、对照组治疗后，大便性状总有效率分别为83.3%、63.3%，腹痛、腹胀症状总有效率分别为90%、66.7%，排便急迫程度总有效率分别为86.7%、60.0%，排便频率总有效率分别为90.0%、63.3%，观察组疗效高于对照组(P<0．05)。两组均未见明显不良反应。结论复方谷氨酰胺肠溶胶囊联合酪酸梭菌治疗IBS-D的临床疗效优于复方谷氨酰胺肠溶胶囊。
目的觀察複方穀氨酰胺腸溶膠囊聯閤酪痠梭菌治療腹瀉型腸易激綜閤徵（IBS-D）的臨床療效。方法120例IBS-D患者，隨機分為觀察組60例，予複方穀氨酰胺腸溶膠囊聯閤酪痠梭菌治療；對照組60例，予複方穀氨酰胺腸溶膠囊治療，兩組均以4w為一療程。結果觀察組總有效率90.0%，對照組總有效率63.3%。觀察組療效高于對照組(P<0．05)；觀察組、對照組治療後，大便性狀總有效率分彆為83.3%、63.3%，腹痛、腹脹癥狀總有效率分彆為90%、66.7%，排便急迫程度總有效率分彆為86.7%、60.0%，排便頻率總有效率分彆為90.0%、63.3%，觀察組療效高于對照組(P<0．05)。兩組均未見明顯不良反應。結論複方穀氨酰胺腸溶膠囊聯閤酪痠梭菌治療IBS-D的臨床療效優于複方穀氨酰胺腸溶膠囊。
목적관찰복방곡안선알장용효낭연합락산사균치료복사형장역격종합정（IBS-D）적림상료효。방법120례IBS-D환자，수궤분위관찰조60례，여복방곡안선알장용효낭연합락산사균치료；대조조60례，여복방곡안선알장용효낭치료，량조균이4w위일료정。결과관찰조총유효솔90.0%，대조조총유효솔63.3%。관찰조료효고우대조조(P<0．05)；관찰조、대조조치료후，대편성상총유효솔분별위83.3%、63.3%，복통、복창증상총유효솔분별위90%、66.7%，배편급박정도총유효솔분별위86.7%、60.0%，배편빈솔총유효솔분별위90.0%、63.3%，관찰조료효고우대조조(P<0．05)。량조균미견명현불량반응。결론복방곡안선알장용효낭연합락산사균치료IBS-D적림상료효우우복방곡안선알장용효낭。
Objective To observe the clinical ef icacy of compound glutamine enteric capsule combined with Clostridium butyricum in treatment of diarrhea type irritable bowel syndrome ( IBS-D ). Methods 120 patients with IBS-D, were randomly divided into two groups. 60 cases in observation group, to compound glutamine enteric capsule combined with Clostridium butyricum treatment; 60 cases in the control group, were treated with compound glutamine enteric capsules. Both the course of the treatment are 4 weeks.Results the total ef ective rate in the observation group is 90% .in control group, the total ef iciency of 63.3%. The therapeutical ef ect of observation group is higher than that of control group ( P<0.05 ); observer group, the control group after treatment, the total ef iciency of stool are respectively 83.3%, 63.3%, the total ef ective rates of abdominal pain, abdominal distension symptoms of were 90%, 66.7%, defecation urgency degree of the total ef ective rates were 86.7%, 60%, defecation frequency total ef ectiveness respectively is 90%, 63.3%, the therapeutical ef ect of observation group is higher than that of control group ( P<0.05 ). The two groups were no obvious adverse reaction.Conclusion The clinical ef icacy of compound glutamine enteric capsules combined with Saccharomyces boulardi is superior to Gubenyichang in the treatment IBS-D.
