CAJ | 학술논문

目的：探讨高血压脑出血患者血浆精氨酸加压素（AVP）水平与患者预后的相关性。方法：对39例高血压脑出血患者定时定量采血，采用放射免疫法测量不同时段血中A V P浓度，治疗后随访3～6个月，并对患者进行日常生活能力标准评分。结果：本组39例高血压脑出血患者发病后24h内血浆AVP含量均显著高于对照组，此后血浆AVP含量呈下降趋势，但直到第9天血浆AVP含量仍显著高于对照组（P＜0．05）。并且预后不良组发病后5天血浆AVP水平持续高于预后良好组（P＜0．05）。结论：急性脑出血后患者血浆AVP含量持续升高而且下降缓慢，提示脑损伤严重，病情迁延，预后不佳。
목적：탐토고혈압뇌출혈환자혈장정안산가압소（AVP）수평여환자예후적상관성。방법：대39례고혈압뇌출혈환자정시정량채혈，채용방사면역법측량불동시단혈중A V P농도，치료후수방3～6개월，병대환자진행일상생활능력표준평분。결과：본조39례고혈압뇌출혈환자발병후24h내혈장AVP함량균현저고우대조조，차후혈장AVP함량정하강추세，단직도제9천혈장AVP함량잉현저고우대조조（P＜0．05）。병차예후불량조발병후5천혈장AVP수평지속고우예후량호조（P＜0．05）。결론：급성뇌출혈후환자혈장AVP함량지속승고이차하강완만，제시뇌손상엄중，병정천연，예후불가。
Objective :To discuss the relationship between the level of plasma arginine vasopressin and prognosis in patients of hypertensive cerebral hemorrhage .Methods:Blood samples of hypertensive cerebral hemor-rhage patients were obtained in time for the measurement of AVP through radioimmunoassay .Results :Of the 39 patients’ group ,the plasma AVP level was significantly higher than the control group’ in the first 24 hours after in-vasion and the plasma AVP level had downtrend in the following days .Conclusion :Continuing rising and slow de-scent of the plasma AVP level after acute cerebral hemorrhage hints serious brain injuries ,protracted course of dis-eases and negative prognosis .