CAJ | 학술논문

低温等离子体的生物学效应包括对微生物的致死作用和对动物细胞的刺激作用，分别造就了一批灭菌技术和临床医药技术。本文介绍了等离子体灭菌技术在医疗器械、水和空气净化、食品和包装材料处理等方面的应用。其中已商业化的医疗器械灭菌器主要分低气压和常压两种，低气压等离子体灭菌器的灭菌体积较大，常压等离子体灭菌器的优点则是结构简单和便于操作。等离子体灭菌技术用于水、空气、食品等领域由于能耗、效率、化学残留等问题尚未商业化。在医药技术方面，近十年来开发的等离子体技术和装备成功运用于龋齿、皮肤、伤口、癌症等的处理，部分已进入临床应用。将来的研究重点在于明确等离子体与细胞之间的相互作用机理，并开发出更高效、实用的用于各相关行业的等离子体技术和装备。
저온등리자체적생물학효응포괄대미생물적치사작용화대동물세포적자격작용，분별조취료일비멸균기술화림상의약기술。본문개소료등리자체멸균기술재의료기계、수화공기정화、식품화포장재료처리등방면적응용。기중이상업화적의료기계멸균기주요분저기압화상압량충，저기압등리자체멸균기적멸균체적교대，상압등리자체멸균기적우점칙시결구간단화편우조작。등리자체멸균기술용우수、공기、식품등영역유우능모、효솔、화학잔류등문제상미상업화。재의약기술방면，근십년래개발적등리자체기술화장비성공운용우우치、피부、상구、암증등적처리，부분이진입림상응용。장래적연구중점재우명학등리자체여세포지간적상호작용궤리，병개발출경고효、실용적용우각상관행업적등리자체기술화장비。
Bio-effects of non-thermal plasma include lethality of microorganisms and stimulation of mammalian cells,which brings up a series of techniques in disinfection and clinical medicine. In this paper,the applications of non-thermal plasma in medical device sterilization,water and air cleaning, as well as food and package treatment are reviewed. Commercialized plasma sterilizer for medical devices can be classified into vacuum and atmospheric pressure,the volume of the former is much larger while the latter is more simple and easy to operate. For disinfection of water,air and food,it is not yet commercialized due to its energy consumption,efficiency or chemical residues. In the last decade , the developed plasma sources and techniques for medicine are successfully applied to treatment of decayed tooth,skin,wound,and cancer,with some of them approved for clinical practice. In the future,the research focus will be identifying the interactions between plasmas and cells,and developing more effective and practical equipment for different applications.