CAJ | 학술논문

目的：探讨妊娠合并下生殖道人乳头瘤病毒（HPV）感染对妊娠结局和新生儿近期影响。方法选择我院2011年1月至2012年1月收治的120例HPV感染孕妇作为观察组，另选取同期HPV检测阴性的正常孕妇100例为对照组，均于分娩时取孕妇羊水、胎儿脐静脉血、胎盘组织及新生儿咽部或外阴分泌物进行HPV检测，分析HPV感染对妊娠结局和新生儿的近期影响。结果观察组阴道分娩率为46.15%，低于对照组的48.98%，但两组比较差异无统计学意义(P>0.05)；两组早产、胎膜早破、胎儿生长受限、产后出血及产褥感染发生率比较差异均无统计学意义(P>0.05)；阴道分娩新生儿羊水、脐静脉血、咽喉或阴道分泌物及胎盘HPV阳性率与剖宫产组比较差异亦均无统计学意义(P>0.05)。结论妊娠合并下生殖道HPV感染对妊娠结局影响不大，且不同分娩方式对新生儿HPV感染无显著影响。
목적：탐토임신합병하생식도인유두류병독（HPV）감염대임신결국화신생인근기영향。방법선택아원2011년1월지2012년1월수치적120례HPV감염잉부작위관찰조，령선취동기HPV검측음성적정상잉부100례위대조조，균우분면시취잉부양수、태인제정맥혈、태반조직급신생인인부혹외음분비물진행HPV검측，분석HPV감염대임신결국화신생인적근기영향。결과관찰조음도분면솔위46.15%，저우대조조적48.98%，단량조비교차이무통계학의의(P>0.05)；량조조산、태막조파、태인생장수한、산후출혈급산욕감염발생솔비교차이균무통계학의의(P>0.05)；음도분면신생인양수、제정맥혈、인후혹음도분비물급태반HPV양성솔여부궁산조비교차이역균무통계학의의(P>0.05)。결론임신합병하생식도HPV감염대임신결국영향불대，차불동분면방식대신생인HPV감염무현저영향。
Objective To analyze the pregnancy outcomes and neonatal immediate impact for the pregnancy complicated with infection of human papillomavirus (HPV) in the genital tract. Methods One hundred twenty pregnant women infected with HPV from Jan. 2011 to Jan. 2012 were enrolled into the study group, another 100 normal pregnant women with negative HPV at the test period were enrolled into the control group. All pregnant women's amniotic fluid, fe-tal umbilical blood, placental tissue and neonatal throat or genital secretions tested by HPV detection when they take birth, then the pregnancy outcomes and neonatal immediate impact for HPV infection were analyzed. Results The study group's vaginal delivery was 46.15%, and lower than the control group's 48.98%, but the difference was not statistically significant;The two groups' preterm, premature rupture of membranes, fetal growth restriction, postpartum hemorrhage and puerperal infection rate showed no significant difference; vaginal delivery newborn amniotic fluid, umbilical cord blood, throat or vaginal secretions and placental HPV-positive rate had no significant difference when compared with the group of cesarean section. Conclusion There is little effect of the pregnancy combined with infection of HPV in the geni-tal tract on pregnancy outcome, as well as the effect of different mode of delivery on neonatal HPV infection.