CAJ | 학술논문

目的研究不同剂量白酒灌服对高脂饮食家兔的血脂、血糖的影响。方法用灌胃白酒及喂饲高脂饮食的方法，观察家兔血清中葡萄糖（GLU）、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白（LDL）、高密度脂蛋白（ HDL）的含量变化。结果不同浓度饮酒均能降低高脂饮食家兔血清TG；低浓度饮酒能轻度降低LDL（P＜0．05）；中浓度饮酒第4周、第8周LDL升高，第12周LDL下降（P＜0．05）；高浓度饮酒LDL明显升高，HDL早期升高后期降低（P＜0．05）；大量饮酒和高脂饮食均显著升高血糖（P＜0．01）。结论适度饮酒能降低高脂饮食所致高脂血症，大量饮酒和高脂饮食导致脂质代谢紊乱及血糖升高。
목적연구불동제량백주관복대고지음식가토적혈지、혈당적영향。방법용관위백주급위사고지음식적방법，관찰가토혈청중포도당（GLU）、총담고순（TC）、감유삼지（TG）、저밀도지단백（LDL）、고밀도지단백（ HDL）적함량변화。결과불동농도음주균능강저고지음식가토혈청TG；저농도음주능경도강저LDL（P＜0．05）；중농도음주제4주、제8주LDL승고，제12주LDL하강（P＜0．05）；고농도음주LDL명현승고，HDL조기승고후기강저（P＜0．05）；대량음주화고지음식균현저승고혈당（P＜0．01）。결론괄도음주능강저고지음식소치고지혈증，대량음주화고지음식도치지질대사문란급혈당승고。
Objective To investigate the effect of drinking different consumptions of Chinese distillate spirits on blood lipid and glucose in high-fat diets rabbits .Methods Rabbits were lavaged with Chinese distillate spirits as well as fed with high-fat diets,and the changes of their serum glucose (GLU),total cholesterol (TC),triglycerides ( TG) ,low-density lipoprotein ( LDL) and high-density lipoprotein ( HDL) levels were observed .Results Drinking different consumptions of Chinese distillate spirits made the levels of TG decreased in high-fat diets rabbits .The levels of LDL decreased slightly in the group of drinking low consumption of Chinese distillate spirits (P<0.05).The levels of LDL increased on the 4 th and 8 th week in the group of drinking moderate consumption of Chinese distillate spirits , but decreased on the 12th week(P<0.05).The levels of LDL increased significantly in the group of drinking high consumption of Chinese distillate spirits ,and the levels of HDL increased in the early stage and declined in the later stage(P<0.05).A large consumption of drinking and high-fat diets both significantly elevated the levels of blood glucose(P<0.01).Conclusion Moderate drinking may reduce hyperlipidemia induced by high-fat diets,heavy drinking and high-fat diets may lead to lipid metabolic disorder and the increase of blood glucose .