国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2014年
2期
85-87
,共3页
艾滋病%抗病毒治疗%效果
艾滋病%抗病毒治療%效果
애자병%항병독치료%효과
AIDS%Antiviral therapy%Therapeutic effect
目的 了解聊城市接受艾滋病高效联合抗反转录病毒治疗病人的基本情况,评估抗病毒治疗效果.方法 病例资料来自于艾滋病综合防治数据信息管理系统,采用回顾性队列研究的方法评估治疗效果.结果 聊城市累计治疗56例病例,治疗12个月后病例病毒抑制率由33.3％提高到86.6％,较治疗前有统计学差异(x2=23.13,P＜0.01).CD4+T淋巴细胞治疗前全部小于350个/μl,治疗24个月后有73.3％的病例≥350个/μl,治疗前后有统计学差异(x2=36.17,P＜0.01).结论 高效联合抗反转录病毒治疗能有效抑制艾滋病病毒复制、提高患者免疫功能.
目的 瞭解聊城市接受艾滋病高效聯閤抗反轉錄病毒治療病人的基本情況,評估抗病毒治療效果.方法 病例資料來自于艾滋病綜閤防治數據信息管理繫統,採用迴顧性隊列研究的方法評估治療效果.結果 聊城市纍計治療56例病例,治療12箇月後病例病毒抑製率由33.3％提高到86.6％,較治療前有統計學差異(x2=23.13,P＜0.01).CD4+T淋巴細胞治療前全部小于350箇/μl,治療24箇月後有73.3％的病例≥350箇/μl,治療前後有統計學差異(x2=36.17,P＜0.01).結論 高效聯閤抗反轉錄病毒治療能有效抑製艾滋病病毒複製、提高患者免疫功能.
목적 료해료성시접수애자병고효연합항반전록병독치료병인적기본정황,평고항병독치료효과.방법 병례자료래자우애자병종합방치수거신식관리계통,채용회고성대렬연구적방법평고치료효과.결과 료성시루계치료56례병례,치료12개월후병례병독억제솔유33.3％제고도86.6％,교치료전유통계학차이(x2=23.13,P＜0.01).CD4+T림파세포치료전전부소우350개/μl,치료24개월후유73.3％적병례≥350개/μl,치료전후유통계학차이(x2=36.17,P＜0.01).결론 고효연합항반전록병독치료능유효억제애자병병독복제、제고환자면역공능.
Objective To analyze the characteristics of HIV/AIDS cases receiving highly active antiretroviral therapy,and evaluate therapeutic effectiveness.Methods The information of the cases was gotten from data information management system for the prevention and control of AIDS.Retrospective cohort study method is used to implement and evaluate therapeutic effect.Results A total of 56 cases were recruited.The viral load suppression rate increased to 86.6％ from 33.3％ after receiving 12 months treatment.There was significant difference between before and after therapy (x2 =23.13,P ＜ 0.01).The CD4 + T lymphocyte were all less than 350/μl before therapy.The CD4 +T lymphocyte in 73.3％ of the cases increased to ≥350/μl after receiving treatment for 24 months.There was significant difference between before and after treatment (x2 =36.17,P ＜0.01).Conclusions Highly active antiretroviral therapy can effectively inhibit HIV replication gradually improve the immune function.
