CAJ | 학술논문

目的探讨去IDA治疗老年AML的临床疗效。方法根据治疗方法不同将42例患者分为观察组和对照组（各21例），观察组给予IDA+Ara-C的联合化疗方案治疗，对照组给予DNR联合Ara-C化疗方案治疗。结果观察组总有效率为90.5%，明显优于对照组的61.9%（ P＜0.05）；两组均有不同程度不良反应出现，但两组不良反应发生率比较差异均无统计学意义（P＞0.05）。结论 IDA是一种治疗老年AML疗效可靠的抗肿瘤药物，具有较高的完全缓解率，可作为缓解老年AML的最佳治疗方案之一。
목적탐토거IDA치료노년AML적림상료효。방법근거치료방법불동장42례환자분위관찰조화대조조（각21례），관찰조급여IDA+Ara-C적연합화료방안치료，대조조급여DNR연합Ara-C화료방안치료。결과관찰조총유효솔위90.5%，명현우우대조조적61.9%（ P＜0.05）；량조균유불동정도불량반응출현，단량조불량반응발생솔비교차이균무통계학의의（P＞0.05）。결론 IDA시일충치료노년AML료효가고적항종류약물，구유교고적완전완해솔，가작위완해노년AML적최가치료방안지일。
Objective To explore the clinical curative effect of the IDA on elderly patients with acute myelogenous leukemia. Methods 42 patients were divided into observation group and control group (21 cases in each group) according to the different treatment methods. The combination chemotherapy treatment of IDA+Ara-C was used in the observation group, and the treatment of DNR combined with chemotherapy of Ara-C was used in the control group. Results The total effective rate of the observation group was 90.5%, which was obviously better than 61.9% of the control group (P < 0.05); adverse reactions of different degree occurred in both groups. However, the incidences of adverse reactions of the two groups had no statistical significance (P>0.05). Conclusion IDA is an antitumor drug with reliable curative effect on elderly patients with acute myelogenous leukemia, which has high complete remission rate and can be one of the best treatments for alleviating elderly patients with acute myelogenous leukemia.