CAJ | 학술논문

戊型肝炎病毒（ HEV）体外细胞培养模型的建立有助于阐明HEV的感染、复制及其致病机理，有利于新型抗病毒药物和疫苗的研发与评估。近年来国内外对HEV细胞培养模型的报道很多，但所用细胞系、感染方法及病毒的复制效果等不尽相同。因此，对近年来HEV细胞培养模型的研究进展进行了综述。
무형간염병독（ HEV）체외세포배양모형적건립유조우천명HEV적감염、복제급기치병궤리，유리우신형항병독약물화역묘적연발여평고。근년래국내외대HEV세포배양모형적보도흔다，단소용세포계、감염방법급병독적복제효과등불진상동。인차，대근년래HEV세포배양모형적연구진전진행료종술。
The development of cell culture models for hepatitis E virus ( HEV) in vitro can help to elucidate the mecha-nisms for HEV infection , replication and pathogenesis , thus promoting the development and evaluation of new antivirus agents and vaccines.In recent years, many studies on HEV cell culture models have been reported , however, these studies showed differences in the cell lines , infecting methods and viral replication effects .This review summarizes the progress on HEV cell culture models .