医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
9期
148-149
,共2页
重症监护病房%葡萄球菌%耐药率
重癥鑑護病房%葡萄毬菌%耐藥率
중증감호병방%포도구균%내약솔
Intensive care Unit%Staphylococcus%Drug resistance
目的：了解虎门镇虎门医院和太平人民医院成人重症监护病房（ICU）病房葡萄球菌耐药情况。方法对我院ICU病房2009年1月-2013年12月送检标本中所分离的葡萄球菌耐药率进行回顾性分析。结果5年间ICU病房共检出葡萄球菌707株，其中金黄色葡萄球菌474株（占67.0%）,耐甲氧西林金黄色葡萄球菌（MRSA）检出率为91.7%；凝固酶阴性葡萄球菌233株（占33.0%），耐甲氧西林凝固酶阴性葡萄球菌（MRCNS）检出率为96.1%。居前三的标本来源为呼吸道、血及伤口分泌物，分别占85.4%，7.8%和4.1%。葡萄球菌对万古霉素、替考拉宁及利奈唑胺全敏感，对利福平、复方新诺明耐药性较低，对其他抗菌药物的耐药性较高。结论 ICU病房葡萄球菌主要来源于呼吸道，MRSA、MRCNS检出率高，且呈多重耐药趋势，应依据药敏结果来选择用药。
目的：瞭解虎門鎮虎門醫院和太平人民醫院成人重癥鑑護病房（ICU）病房葡萄毬菌耐藥情況。方法對我院ICU病房2009年1月-2013年12月送檢標本中所分離的葡萄毬菌耐藥率進行迴顧性分析。結果5年間ICU病房共檢齣葡萄毬菌707株，其中金黃色葡萄毬菌474株（佔67.0%）,耐甲氧西林金黃色葡萄毬菌（MRSA）檢齣率為91.7%；凝固酶陰性葡萄毬菌233株（佔33.0%），耐甲氧西林凝固酶陰性葡萄毬菌（MRCNS）檢齣率為96.1%。居前三的標本來源為呼吸道、血及傷口分泌物，分彆佔85.4%，7.8%和4.1%。葡萄毬菌對萬古黴素、替攷拉寧及利奈唑胺全敏感，對利福平、複方新諾明耐藥性較低，對其他抗菌藥物的耐藥性較高。結論 ICU病房葡萄毬菌主要來源于呼吸道，MRSA、MRCNS檢齣率高，且呈多重耐藥趨勢，應依據藥敏結果來選擇用藥。
목적：료해호문진호문의원화태평인민의원성인중증감호병방（ICU）병방포도구균내약정황。방법대아원ICU병방2009년1월-2013년12월송검표본중소분리적포도구균내약솔진행회고성분석。결과5년간ICU병방공검출포도구균707주，기중금황색포도구균474주（점67.0%）,내갑양서림금황색포도구균（MRSA）검출솔위91.7%；응고매음성포도구균233주（점33.0%），내갑양서림응고매음성포도구균（MRCNS）검출솔위96.1%。거전삼적표본래원위호흡도、혈급상구분비물，분별점85.4%，7.8%화4.1%。포도구균대만고매소、체고랍저급리내서알전민감，대리복평、복방신낙명내약성교저，대기타항균약물적내약성교고。결론 ICU병방포도구균주요래원우호흡도，MRSA、MRCNS검출솔고，차정다중내약추세，응의거약민결과래선택용약。
OBJECTIVES To investigate drug resistance of Staphylococcus from intensive care unit(ICU) in our hospital. METHODS A retrospective analysis of drug sensitivity test of Staphylococcus in ICU from Jan,2009 to Dec,2013 were col ected.RESULTS There were 707 strains of Staphylococcus in 5 years,including 474 strains staphylococcus aureus, of which 91.7% were methicil in-resistant staphylococcus aureus(MRSA) and 233 strains coagulase negative staphylococcus,of which 96.1% were methicil in-resistant coagulase negative staphylococcus(MRCNS).The pathogens were isolated from the respiratory tract(85.4%), bloodstream(7.8%) and wound (4.1%). Staphylococcus were 100% sensitive to vancomycin,linezolid and teicoplanin and it showed low rates of resistance to rifampicin and sulfamethoxazole.However the resistance rate of other antibiotics were high. CONCLUSION ICU infection of Staphylococcus were most common in the respiratory tract. The relevance ratio of MRSA and MRCNS were high and they showed multi-drug resistance tendency. It should be based on the susceptibility patterns to the choice of drugs.
