CAJ | 학술논문

目的：观察巴曲酶（东菱克栓酶）联用低分子量肝素治疗急性脑梗死的疗效。方法治疗组30例患者采用巴曲酶和低分子量肝素治疗；对照组30例单用低分子量肝素。二组患者其他常规治疗对症处理相同。比较二组疗效和患者治疗前后血液流变性的变化。结果治疗组基本治愈率和总显效率为66．7％和86．7％，对照组分别为30％和63．3％。治疗组基本痊愈率和总显效率显著优于对照组（P＜0．01和P＜0．05）。治疗后治疗组血流变学指标的改善均优于对照组（P＜0．05）。结论联用巴曲酶和低分子量肝素治疗中老年急性脑梗死早期见效快，作用稳定，无明显不良反应，值得推广。
목적：관찰파곡매（동릉극전매）련용저분자량간소치료급성뇌경사적료효。방법치료조30례환자채용파곡매화저분자량간소치료；대조조30례단용저분자량간소。이조환자기타상규치료대증처리상동。비교이조료효화환자치료전후혈액류변성적변화。결과치료조기본치유솔화총현효솔위66．7％화86．7％，대조조분별위30％화63．3％。치료조기본전유솔화총현효솔현저우우대조조（P＜0．01화P＜0．05）。치료후치료조혈류변학지표적개선균우우대조조（P＜0．05）。결론련용파곡매화저분자량간소치료중노년급성뇌경사조기견효쾌，작용은정，무명현불량반응，치득추엄。
Objective To investigate the efficacy of Batroxobin with low molecular weight heparin(LMWH)on the treatment of acute cerebral infarction.Methods 60 cases were randomly divided into two groups.The 30 patients in the treated group were treated with Batroxo-bin and LMWH,and the other 30 patients in the control group were treated by LMWH,the same other conventinal treatment was used in two groups.The treatment efficacy and the changes in blood rheology and symptometic score at different times were obsevered.Results The basi-cally Cured rate and the total effective rate were 66.7%and 86.7%in the treated group.The control group were 30%and 63.3%.In Com-parison between two groups the differens in basically cured and total effective rates were significant(P<0.01 and P<0.05).After clinical treatment,the changes of hemorheological parameters in the treated group were bellow than the controls(P<0.05 ).Conclusion It is safe and rapidly effective for batroxobin with LMWH in the treatment of acute cerebral infarction.There is not obviously harmful reactions and it is worth spread to use.