CAJ | 학술논문

目的：观察马来酸依那普利叶酸片（简称依叶）治疗非ST段抬高急性心肌梗死PCI术后的疗效是否优于马来酸依那普利片。方法：选择NSTEMI患者经三级医院PCI治疗后再转入我院后续治疗的50例为实验组，对照组为既往在我院接受治疗的患者50例，实验组口服依那普利叶酸片10mg/d ，对照组单一依那普利片10mg/d口服，持续3个月～1年；观察两组患者治疗前、后血浆 HCY、血压、血糖对比，治疗前、后做常规18导联心电图，观察18导联上ST段压低总和。结果：在ST段改善方面，实验组比对照组改善明显；在心衰发生情况方面，实验组7例出现心衰，占14．0％，对照组16例出现心衰，占32．0％；在死亡率方面，实验组3例死亡，发生率为6．0％，对照组6例死亡，发生率为12．0％，三项比较均具有统计学意义（P＜0．05）。两组在治疗前、后的组内、组间比较血浆 HCY具有统计学意义（P＜0．05）、血压在治疗前、后的组内比较均具有统计学意义（P＜0．05），而在组间比较无统计学意义（P＞0．05），血糖在治疗前、后的组内、组间比较均无统计学意义（P＞0．05）。结论：依那普利叶酸片治疗非ST段抬高急性心肌梗死PCI术后，后续治疗方面具有改善心肌缺血、降压和降 HCY水平效果显著，同时还可以减少心衰等并发症及死亡率。
목적：관찰마래산의나보리협산편（간칭의협）치료비ST단태고급성심기경사PCI술후적료효시부우우마래산의나보리편。방법：선택NSTEMI환자경삼급의원PCI치료후재전입아원후속치료적50례위실험조，대조조위기왕재아원접수치료적환자50례，실험조구복의나보리협산편10mg/d ，대조조단일의나보리편10mg/d구복，지속3개월～1년；관찰량조환자치료전、후혈장 HCY、혈압、혈당대비，치료전、후주상규18도련심전도，관찰18도련상ST단압저총화。결과：재ST단개선방면，실험조비대조조개선명현；재심쇠발생정황방면，실험조7례출현심쇠，점14．0％，대조조16례출현심쇠，점32．0％；재사망솔방면，실험조3례사망，발생솔위6．0％，대조조6례사망，발생솔위12．0％，삼항비교균구유통계학의의（P＜0．05）。량조재치료전、후적조내、조간비교혈장 HCY구유통계학의의（P＜0．05）、혈압재치료전、후적조내비교균구유통계학의의（P＜0．05），이재조간비교무통계학의의（P＞0．05），혈당재치료전、후적조내、조간비교균무통계학의의（P＞0．05）。결론：의나보리협산편치료비ST단태고급성심기경사PCI술후，후속치료방면구유개선심기결혈、강압화강 HCY수평효과현저，동시환가이감소심쇠등병발증급사망솔。
Objective :Observation of enalapril maleate and folic acid tablets (hereinafter referred to as leaf ) the effect of treating non-ST segment elevation acute myocardial infarction patients after PCI is better than that of enalapril mal-eate tablets .Methods :Patients with NSTEMI grade three hospital after PCI therapy to 50 cases in our hospital follow-up treatment ,control group 50 cases of patients treated in our hospital ,the experimental group ,enalapril folic acid tab-lets 10mg/d ,while the control group only enalapril 10mg/d orally ,for 3 months to 1 year ;two groups were observed before and after patients treated with plasma HCY ,blood pressure ,blood sugar comparative before and after treatment , routine 18 lead ECG ,observation of 18 lead ST segment depression sum .Results:The improvements in the ST segment , the experimental group was significantly better than the control group improved ;in heart failure ,7 cases in the experi-mental group had heart failure ,accounting for 14 .0% ,16 cases in the control group had heart failure ,accounting for 32 .0% ;in terms of mortality ,experimental group 3 cases died ,the incidence rate was 6 .0% ,the control group of 6 ca-ses of death ,the incidence rate was 12 .0% ,three were statistically significant (P<0 .05) .The two groups before and after treatment group ,compared with plasma HCY with statistical significance (P<0 .05) ,blood pressure before and after treatment were compared with the group with statistical significance (P<0 .05) ,but no statistical significance in the group (P>0 .05) ,blood glucose before and after treatment in the group ,the comparison among groups had no sta-tistical significance (P>0 .05) .Conclusion:Enalapril folic acid tablets in treatment of non-ST segment elevation acute myocardial infarction after PCI ,the follow-up treatment can improve myocardial ischemia ,reduction of blood pressure and HCY level significantly ,but also can reduce the complications and mortality in heart failure .