北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
4期
64-64,65
,共2页
安然%穆欣华%秦广平%李春艳
安然%穆訢華%秦廣平%李春豔
안연%목흔화%진엄평%리춘염
地佐辛%超前镇痛%临床%综述
地佐辛%超前鎮痛%臨床%綜述
지좌신%초전진통%림상%종술
Dezocine%Preemptive analgesia%Clinic%Summarize
地佐辛是一种新型阿片类镇痛药,是k受体激动剂,也是μ受体拮抗剂,对μ受体有部分激动作用,但不产生典型的μ受体依赖[1,2],其镇痛强度、起效时间和作用持续时间与吗啡相当,呼吸抑制轻,药物依赖发生率较低,近年来已用于临床麻醉镇痛。本文参阅了近年来地佐辛在临床领域超前镇痛的文献进行综述。
地佐辛是一種新型阿片類鎮痛藥,是k受體激動劑,也是μ受體拮抗劑,對μ受體有部分激動作用,但不產生典型的μ受體依賴[1,2],其鎮痛彊度、起效時間和作用持續時間與嗎啡相噹,呼吸抑製輕,藥物依賴髮生率較低,近年來已用于臨床痳醉鎮痛。本文參閱瞭近年來地佐辛在臨床領域超前鎮痛的文獻進行綜述。
지좌신시일충신형아편류진통약,시k수체격동제,야시μ수체길항제,대μ수체유부분격동작용,단불산생전형적μ수체의뢰[1,2],기진통강도、기효시간화작용지속시간여마배상당,호흡억제경,약물의뢰발생솔교저,근년래이용우림상마취진통。본문삼열료근년래지좌신재림상영역초전진통적문헌진행종술。
Dezocine, is a new type of opioid agonist is k, is also mu receptor antagonist, for mu receptor is part of the excitement, but do not produce the typical mu receptor [1,2], the analgesia strength, working time and duration with morphine, respiratory depression light, lower incidence of drug dependence, in recent years has been used in clinical anesthesia analgesia. This article reviewed in recent years with sheen the literature review of advance in the field of clinical analgesia.