CAJ | 학술논문

目的研究里尔统（磷酸肌酸钠，简称CP）在早期舒张功能障碍逆转治疗中的疗效。方法用彩色多普勒测量 E/A比值，Ea/Aa比值，E/Ea比值及临床表现筛查舒张功能早期障碍的病人109例，并以自身对照的方式进行观察。治疗方式，常规治疗原发病同时轻度舒张功能减低者CP2g＋5％葡萄糖或0．9％的氯化钠100ml静脉滴注，每天一次，连续7-14天为一疗程；中度舒张功能减退者CP2g＋5％葡萄糖或0．9％的氯化钠100ml静脉滴注，每天两次，连续7-14天为一疗程。结果治疗后患者的临床症状和体征明显改善，有统计学意义。结论里尔统（ CP）对改善临床症状和体征，改善原发疾病，逆转心脏舒张功能障碍具有显著的临床疗效，细致入微的护理在患者的康复中起着重要作用。
목적연구리이통（린산기산납，간칭CP）재조기서장공능장애역전치료중적료효。방법용채색다보륵측량 E/A비치，Ea/Aa비치，E/Ea비치급림상표현사사서장공능조기장애적병인109례，병이자신대조적방식진행관찰。치료방식，상규치료원발병동시경도서장공능감저자CP2g＋5％포도당혹0．9％적록화납100ml정맥적주，매천일차，련속7-14천위일료정；중도서장공능감퇴자CP2g＋5％포도당혹0．9％적록화납100ml정맥적주，매천량차，련속7-14천위일료정。결과치료후환자적림상증상화체정명현개선，유통계학의의。결론리이통（ CP）대개선림상증상화체정，개선원발질병，역전심장서장공능장애구유현저적림상료효，세치입미적호리재환자적강복중기착중요작용。
Objective Aim The curative effect of Neoton(CP)in the reversible treatment at early stage of diastolic dysfunction.Methods 109 patients with diastolic dysfunction at early stage have been screened by Doppler measurements including E/A,Ea/Aa,E/Ea as well as clinical signs.The observation is under self-compari-son.Treatment First of all,routine treatment of the primary disease is necessary;Mild diastolic dysfunction is using CP 2g+5%G.S or CP 2g+0.9%N.S 100ml,iV. drip,Qd,Duration 7-14days;Moderate diastolic dysfunction is using CP 2g+5%G.S or CP 2g+0.9%N.S 100ml,iV.drip,Bid,Duration 7-14days.Results CP can obviously improve not only symptoms but also signs of diastolic dysfunction .This study shows statistical significance .Conclusion CP is effective to treat primary disease and improve symptoms and signs of diastolic dysfunction.Moreover,CP shows notable clinical curative effect on reversion of cardiac diastolic dysfunction.