现代消化及介入诊疗
現代消化及介入診療
현대소화급개입진료
MODERN DIGESTION & INTERVENTION
2013年
3期
148-151
,共4页
认知行为疗法%非糜烂性反流病%疑病症%雷贝拉唑
認知行為療法%非糜爛性反流病%疑病癥%雷貝拉唑
인지행위요법%비미란성반류병%의병증%뢰패랍서
Cognitive behavioral therapy%Non-erosive reflux disease%Hypochondriasis%Rabeprazole
目的观察认知行为疗法在治疗非糜烂性反流病合并疑病症患者的临床疗效。方法将42例非糜烂性反流病合并疑病症患者随机分为治疗组21例和对照组21例,对照组采用雷贝拉唑10 mg,po, bid、多潘立酮10 mg,po,tid治疗(常规治疗),治疗组在对照组治疗的基础上,实施认知行为疗法治疗,两组疗程均为8周,比较两组治疗后症状缓解、RDQ问卷评分、症状自评量表(SCL-90)评分及明尼苏达多项人格测验(MMPI)改善情况。结果经治疗8周后,对照组中显效28.6%,总有效率47.6%;治疗组中显效61.9%,总有效率85.7%,两组总有效率差异有显著性(P<0.05);治疗前,治疗组与对照组在RDQ问卷评分、SCL-90评分及MMPI评分方面相比差异均无显著性(P>0.05),其中SCL-90评分有3个因子>2分,包括强迫、焦虑、抑郁因子,提示患者处于强迫、焦虑、抑郁状态,但从病情程度来看,未达强迫症、焦虑神经症、抑郁神经症诊断参照标准;经治疗8周后,治疗组与对照组在RDQ问卷评分、SCL-90评分及MMPI评分的T分,如疑病、抑郁、癔症、精神病态、偏执、精神衰弱方面相比差异有显著性,具有统计学意义(P<0.05)。结论认知行为疗法可以显著改善非糜烂性反流病合并疑病症患者的胃食管反流症状,同时明显改善患者疑病、焦虑、抑郁等心理障碍,明显提高患者生活质量,值得临床推广。
目的觀察認知行為療法在治療非糜爛性反流病閤併疑病癥患者的臨床療效。方法將42例非糜爛性反流病閤併疑病癥患者隨機分為治療組21例和對照組21例,對照組採用雷貝拉唑10 mg,po, bid、多潘立酮10 mg,po,tid治療(常規治療),治療組在對照組治療的基礎上,實施認知行為療法治療,兩組療程均為8週,比較兩組治療後癥狀緩解、RDQ問捲評分、癥狀自評量錶(SCL-90)評分及明尼囌達多項人格測驗(MMPI)改善情況。結果經治療8週後,對照組中顯效28.6%,總有效率47.6%;治療組中顯效61.9%,總有效率85.7%,兩組總有效率差異有顯著性(P<0.05);治療前,治療組與對照組在RDQ問捲評分、SCL-90評分及MMPI評分方麵相比差異均無顯著性(P>0.05),其中SCL-90評分有3箇因子>2分,包括彊迫、焦慮、抑鬱因子,提示患者處于彊迫、焦慮、抑鬱狀態,但從病情程度來看,未達彊迫癥、焦慮神經癥、抑鬱神經癥診斷參照標準;經治療8週後,治療組與對照組在RDQ問捲評分、SCL-90評分及MMPI評分的T分,如疑病、抑鬱、癔癥、精神病態、偏執、精神衰弱方麵相比差異有顯著性,具有統計學意義(P<0.05)。結論認知行為療法可以顯著改善非糜爛性反流病閤併疑病癥患者的胃食管反流癥狀,同時明顯改善患者疑病、焦慮、抑鬱等心理障礙,明顯提高患者生活質量,值得臨床推廣。
목적관찰인지행위요법재치료비미란성반류병합병의병증환자적림상료효。방법장42례비미란성반류병합병의병증환자수궤분위치료조21례화대조조21례,대조조채용뢰패랍서10 mg,po, bid、다반립동10 mg,po,tid치료(상규치료),치료조재대조조치료적기출상,실시인지행위요법치료,량조료정균위8주,비교량조치료후증상완해、RDQ문권평분、증상자평량표(SCL-90)평분급명니소체다항인격측험(MMPI)개선정황。결과경치료8주후,대조조중현효28.6%,총유효솔47.6%;치료조중현효61.9%,총유효솔85.7%,량조총유효솔차이유현저성(P<0.05);치료전,치료조여대조조재RDQ문권평분、SCL-90평분급MMPI평분방면상비차이균무현저성(P>0.05),기중SCL-90평분유3개인자>2분,포괄강박、초필、억욱인자,제시환자처우강박、초필、억욱상태,단종병정정도래간,미체강박증、초필신경증、억욱신경증진단삼조표준;경치료8주후,치료조여대조조재RDQ문권평분、SCL-90평분급MMPI평분적T분,여의병、억욱、억증、정신병태、편집、정신쇠약방면상비차이유현저성,구유통계학의의(P<0.05)。결론인지행위요법가이현저개선비미란성반류병합병의병증환자적위식관반류증상,동시명현개선환자의병、초필、억욱등심리장애,명현제고환자생활질량,치득림상추엄。
Objective To observe the clinical effectiveness of the cognitive behavioral therapy (CBT) in the treatment of patients with non-erosive reflux disease (NERD) combined hypochondriasis. Methods Forty two patients with NERD combined with hypochondriasis were randomly assigned into two groups: treatment group (n=21)and control group (n=21). Patients in control group were treated with rabeprazole (10 mg po. bid), domperidone (10 mg po.tid) (conventional treatment). While patients in treatment group was added with (CBT) . The treatment period was eight weeks. The symptom scale, reflux diagnostic questionnare (RDQ) scale , SCL-90 scale, and MMPI scale were compared. Results After 8-week treatment,there were significant dif-ferences between the two groups on main symptoms, with total effective rate of 85.7%in treatment group and 47.6%in control group (P<0.05). There were no significant difference between the two groups on RDQ scores, SCL-90 score and MMPI score before treatment (P>0.05). However, after 8-week treatment, there were sig-nificant differences between the two groups on RDQ scores, SCL-90 score, and T points of MMPI such as hypochondria, depression, hysteria, psychopathic deviate, paranoia and psychasthenia (P<0.05). Conclusion CBT could significantly improve the gastroesophageal reflux symptoms of patients with NERD combined with hypochondriasis, and at the same time could significantly improve the mood disorder of patients.