CAJ | 학술논문

目的观察术前中药辨证调理对老年人术后近期认知功能障碍（POCD）的预防作用。方法择期行全髋关节置换手术的老年患者46例，随机分为2组：观察组和对照组，每组23例。记录患者术前1d、术后第1天和第7天的简易智能量表（MMSE）得分。结果对照组术后第1天及第7天的MMSE评分较术前降低（P＜0.05），而观察组术后第1天及第7天的MMSE评分与术前的评分差异无统计学意义（P＞0.05）。观察组术后第1d出现认知功能受损的比例（9%）较对照组（35%）低（P＜0.05）；术后第7天出现认知功能受损的比例分别为4%和17%，但差异无统计学意义（P＞0.05）。结论术前中药辨证调理对老年人髋关节置换术后近期认知功能障碍有预防作用。
목적관찰술전중약변증조리대노년인술후근기인지공능장애（POCD）적예방작용。방법택기행전관관절치환수술적노년환자46례，수궤분위2조：관찰조화대조조，매조23례。기록환자술전1d、술후제1천화제7천적간역지능량표（MMSE）득분。결과대조조술후제1천급제7천적MMSE평분교술전강저（P＜0.05），이관찰조술후제1천급제7천적MMSE평분여술전적평분차이무통계학의의（P＞0.05）。관찰조술후제1d출현인지공능수손적비례（9%）교대조조（35%）저（P＜0.05）；술후제7천출현인지공능수손적비례분별위4%화17%，단차이무통계학의의（P＞0.05）。결론술전중약변증조리대노년인관관절치환술후근기인지공능장애유예방작용。
Objective To observe the preventive effect of recent postoperative cognitive dysfunction(POCD)on the aged with traditional Chinese medicine (TCM) differential treatment. Methods Forty six elderly patients undergoing elective total hip replacement surgery were randomly allocated into two groups (n=23)according to the treatment:observation group and control group. The mini-mental state examination (MMSE)scores of all the patients were recorded one day before surgery,one day and seven days after surgery. Results The MMSE scores of the control group on the first day and the seventh day after surgery were both lower than that before surgery (P<0. 05),but the difference of MMSE scores were not statistically significant in the observation group(P>0. 05). The incidence of cognitive impairment on the first day after surgery in the observation group (9%) was lower than that in the observation group (35%)(P<0. 05). The difference of the incidence of cognitive impairment on the seventh day after surgery was not statistically significant between the two groups (P>0. 05). Conclusion The recent POCD can be prevented by the TCM differential treatment on the aged people before hip replacement surgery.