东南大学学报（医学版）
東南大學學報（醫學版）
동남대학학보（의학판）
JOURNAL OF SOUTHEAST UNIVERSITY(MEDICAL SCIENCE EDITION)
2013年
4期
389-393
,共5页
SHEKHAR Kumar Mehta%刘万花
SHEKHAR Kumar Mehta%劉萬花
SHEKHAR Kumar Mehta%류만화
乳腺磁共振成像%增强磁共振成像%磁共振血管成像%患侧血管增加%病灶邻近血管%最大信号投影
乳腺磁共振成像%增彊磁共振成像%磁共振血管成像%患側血管增加%病竈鄰近血管%最大信號投影
유선자공진성상%증강자공진성상%자공진혈관성상%환측혈관증가%병조린근혈관%최대신호투영
breast magnetic resonance imaging%contrast-enhanced magnetic resonance imaging%MR angiography%ipsilateral increased vascularity%adjacent vessel sign%maximum-intensity projection
目的：回顾性评估3．0 T动态增强MR血管成像（ MRA ）对乳腺良恶性病变的诊断价值。方法：经病理证实的108例乳腺疾病患者（52例恶性，56例良性）作为研究对象，借助3D MRA图像计算患侧血管增加（双侧差异血管数≥2）及病变邻近血管数。结果：52例乳腺恶性病变中41例、56例良性病变中9例出现患侧血管增加，以患侧血管增加作为诊断标准，其对乳腺恶性病变诊断的敏感性、特异性及准确度分别79％、84％及84％；52例乳腺恶性病变中46例、56例良性病变中18例出现病灶邻近血管，以病灶邻近血管作为诊断标准，其对乳腺恶性病变诊断的敏感性、特异性及准确度分别为89％、68％及76％；患侧血管增加的阳性预测值及阴性预测值分别为82％、81％，病灶邻近血管的阳性预测值及阴性预测值分别为82％、79％。结论：3 D MRA能有效评估双侧乳腺血管形成。乳腺恶性病变比良性病变更容易出现患侧血管增加及病灶邻近血管。
目的：迴顧性評估3．0 T動態增彊MR血管成像（ MRA ）對乳腺良噁性病變的診斷價值。方法：經病理證實的108例乳腺疾病患者（52例噁性，56例良性）作為研究對象，藉助3D MRA圖像計算患側血管增加（雙側差異血管數≥2）及病變鄰近血管數。結果：52例乳腺噁性病變中41例、56例良性病變中9例齣現患側血管增加，以患側血管增加作為診斷標準，其對乳腺噁性病變診斷的敏感性、特異性及準確度分彆79％、84％及84％；52例乳腺噁性病變中46例、56例良性病變中18例齣現病竈鄰近血管，以病竈鄰近血管作為診斷標準，其對乳腺噁性病變診斷的敏感性、特異性及準確度分彆為89％、68％及76％；患側血管增加的暘性預測值及陰性預測值分彆為82％、81％，病竈鄰近血管的暘性預測值及陰性預測值分彆為82％、79％。結論：3 D MRA能有效評估雙側乳腺血管形成。乳腺噁性病變比良性病變更容易齣現患側血管增加及病竈鄰近血管。
목적：회고성평고3．0 T동태증강MR혈관성상（ MRA ）대유선량악성병변적진단개치。방법：경병리증실적108례유선질병환자（52례악성，56례량성）작위연구대상，차조3D MRA도상계산환측혈관증가（쌍측차이혈관수≥2）급병변린근혈관수。결과：52례유선악성병변중41례、56례량성병변중9례출현환측혈관증가，이환측혈관증가작위진단표준，기대유선악성병변진단적민감성、특이성급준학도분별79％、84％급84％；52례유선악성병변중46례、56례량성병변중18례출현병조린근혈관，이병조린근혈관작위진단표준，기대유선악성병변진단적민감성、특이성급준학도분별위89％、68％급76％；환측혈관증가적양성예측치급음성예측치분별위82％、81％，병조린근혈관적양성예측치급음성예측치분별위82％、79％。결론：3 D MRA능유효평고쌍측유선혈관형성。유선악성병변비량성병변경용역출현환측혈관증가급병조린근혈관。
Objective:To retrospectively assess the use of 3.0 T contrast-enhanced MR angiography (MRA) in differentiating benign from malignant breast lesions .Materials and Methods: This retrospective study enrolled total of 108 patients with unilateral and histopathologically confirmed breast lesions ( 52 malignant lesions and 56 benign lesions ) which were evaluated for ipsilateral increased vascularity and the presence of adjacent vessel sign by contrast-enhanced 3 D MR angiograms .Results:Forty-one out of 52 patients with breast cancer and 9 out of 56 patients with benign lesions , ipsilateral increased breast vascularity was found .The resulting sensitivity and specificity of ipsilateral increased vascularity were 79% and 84% respectively .The adjacent vessel sign ( AVS ) was present in 46 of the 52 patients with breast cancer and 18 of the 56 patients with benign lesions .The resulting sensitivity and specificity of the adjacent vessel sign were 89% and 68% respectively .The accuracy of ipsilateral increased vascularity and the AVS were 84% and 76%.The positive predictive value ( PPV ) and negative predictive value ( NPV) for ipsilateral increased vascularity were 82%and 81%and for AVS were 71%and 86%respectively .Overall accuracies were 82% and 79%.Conclusion: It can be concluded that MR angiograms generated from dynamic contrast enhanced 3 D MR images can be used successfully in evaluation of breast vascularity .Ipsilateral increased vascularity and the AVS were strongly associated with breast cancer .
