皮肤性病诊疗学杂志
皮膚性病診療學雜誌
피부성병진료학잡지
DIAGNOSIS AND THERAPY JOURNAL OF DERMATO-VENEREOLOGY
2013年
4期
246-248
,共3页
系统性红斑狼疮%维生素D%缺乏
繫統性紅斑狼瘡%維生素D%缺乏
계통성홍반랑창%유생소D%결핍
Systemic lupus erythematosus%Vitamin D%Deficiency
目的：探讨花都地区系统性红斑狼疮（ sytemic lupus erythematosus，SLE）患者维生素D水平变化情况。方法：收集我院皮肤科门诊SLE患者56例，分别检测血清Ca、P、ALP、iPTH和25（OH）D3水平，与同期皮肤科门诊非SLE患者55例的相关指标进行比较。结果：与对照组比较，SLE患者血清Ca、P、ALP和iPTH水平无明显差异（P值均＞0.05），血清25（OH）D3水平明显下降（t＝3.65，P＜0.01）， SLE患者维生素D水平不足及缺乏的患者比例明显增多（礸2＝13.12，P＜0.01）；SLE患者维生素D水平不足和缺乏在阳光较强季节组和阳光较弱季节组差异均无统计学意义（ P值均＞0.05）。结论：花都地区SLE患者维生素D水平降低，临床上应监测及适当补充维生素D治疗。
目的：探討花都地區繫統性紅斑狼瘡（ sytemic lupus erythematosus，SLE）患者維生素D水平變化情況。方法：收集我院皮膚科門診SLE患者56例，分彆檢測血清Ca、P、ALP、iPTH和25（OH）D3水平，與同期皮膚科門診非SLE患者55例的相關指標進行比較。結果：與對照組比較，SLE患者血清Ca、P、ALP和iPTH水平無明顯差異（P值均＞0.05），血清25（OH）D3水平明顯下降（t＝3.65，P＜0.01）， SLE患者維生素D水平不足及缺乏的患者比例明顯增多（礸2＝13.12，P＜0.01）；SLE患者維生素D水平不足和缺乏在暘光較彊季節組和暘光較弱季節組差異均無統計學意義（ P值均＞0.05）。結論：花都地區SLE患者維生素D水平降低，臨床上應鑑測及適噹補充維生素D治療。
목적：탐토화도지구계통성홍반랑창（ sytemic lupus erythematosus，SLE）환자유생소D수평변화정황。방법：수집아원피부과문진SLE환자56례，분별검측혈청Ca、P、ALP、iPTH화25（OH）D3수평，여동기피부과문진비SLE환자55례적상관지표진행비교。결과：여대조조비교，SLE환자혈청Ca、P、ALP화iPTH수평무명현차이（P치균＞0.05），혈청25（OH）D3수평명현하강（t＝3.65，P＜0.01）， SLE환자유생소D수평불족급결핍적환자비례명현증다（찰2＝13.12，P＜0.01）；SLE환자유생소D수평불족화결핍재양광교강계절조화양광교약계절조차이균무통계학의의（ P치균＞0.05）。결론：화도지구SLE환자유생소D수평강저，림상상응감측급괄당보충유생소D치료。
Objective:To measure vitamin D level in patients with systemic lupus erythemato-sus (SLE) in Huadu area.Methods:56 patients with SLE,55 gender and age-matched controls were recruited from our out-patient department since January , 2009 to December , 2011 .The level of serum Ca , P and ALP were measured by auto-biochemical analyzer , and the levels of serum iPTH and 25-hydroxyvitamin D (25(OH)D3) were measured by ELISA.Results:Compared with the control group , the level of serum Ca , P, ALP and iPTH were not significant different ( P>0.05), while the level of 25(OH)D3 was lower (t=3.65, P<0.01).The ratio of vitamin D in-suficiency and deficiency in SLE group was significantly higher than that in control group (X2 =13.12,P<0.01).Between the SLE groups in mild sunny season and in intense sunny season , the difference of the ratio of vitamin D insuficiency and deficiency has no statistically significant . Conclusion:Even in sunny Huadu area , the patients with SLE had vitamin D deficiency or insuffi-ciency.Monitoring and replenishing vitamin D is an indispensable strategy for SLE treatment .
