CAJ | 학술논문

目的探讨自拟中医药口服方，灌肠方，沐浴方及穴位按摩联合运用的四位一体，全方位，多靶点综合干预技术，观察治疗CRF患者的临床疗效。方法符合纳入CRF标准的患者随机分为治疗组（实施中医药四位一体干预技术组）和对照组（口服西药包醛氧淀粉组）；观察二组患者客观症状的改善，肌酐（Scr）、尿素氮（Bun），内生肌酐清除率（Ccr）等生化指标变化，评定疗效。结果经3个疗程90 d的治疗比较，治疗组和对照组CRF患者的Scr，Bun，Ccr变化进行比较有极其显著差异P﹤0.01）。结论四位一体综合干预技术防治CRF疗效显著，值得临床推广应用。
목적탐토자의중의약구복방，관장방，목욕방급혈위안마연합운용적사위일체，전방위，다파점종합간예기술，관찰치료CRF환자적림상료효。방법부합납입CRF표준적환자수궤분위치료조（실시중의약사위일체간예기술조）화대조조（구복서약포철양정분조）；관찰이조환자객관증상적개선，기항（Scr）、뇨소담（Bun），내생기항청제솔（Ccr）등생화지표변화，평정료효。결과경3개료정90 d적치료비교，치료조화대조조CRF환자적Scr，Bun，Ccr변화진행비교유겁기현저차이P﹤0.01）。결론사위일체종합간예기술방치CRF료효현저，치득림상추엄응용。
Objective:To investigate the multi-target comprehensive intervention technology with the combined quaternity use of traditional chinese medicine oral administration, enema prescription, bath lotion and point massage and observe the clinical efficacy in patients with CRF. Methods:The patients with CRF were randomly divided into treatment group implemented with the quaternity intervention technology and control group given with western medicine aldehyde oxide starch, and the curative effects were estimated by observing objective symptoms improvement and the change of biochemical index including Scr, Bun and Ccr of the patients in two groups. Results: The results showed that there were significant differences between two groups in the improvement of Scr, Bun, Ccr (P﹤0.01) of the patents after 3 courses (90 days) of treatments. Conclusion:It could be concluded that the quaternity intervention technology is significantly effective in prevention and control of CRF, and worthy of clinical application.