暨南大学学报（自然科学与医学版）
暨南大學學報（自然科學與醫學版）
기남대학학보（자연과학여의학판）
JOURNAL OF JINAN UNIVERSITY（NATURAL SCIENCE & MEDICINE EDITION）
2013年
4期
441-444
,共4页
张潇艺%邓列华%胡云峰%赵刚%刘赛君%孙乐栋%罗育武%谢明%金泓
張瀟藝%鄧列華%鬍雲峰%趙剛%劉賽君%孫樂棟%囉育武%謝明%金泓
장소예%산렬화%호운봉%조강%류새군%손악동%라육무%사명%금홍
复发性生殖器疱疹%盐酸伐昔洛韦片%匹多莫德片
複髮性生殖器皰疹%鹽痠伐昔洛韋片%匹多莫德片
복발성생식기포진%염산벌석락위편%필다막덕편
recurrent genital herpes%valaciclovir hydrochloride tablets%pidotimod tablets
目的：评价口服盐酸伐昔洛韦片联合口服匹多莫德片治疗复发性生殖器疱疹的临床疗效。方法：选择复发性生殖器疱疹患者88例，随机分为两组，治疗组45例，对照组43例。治疗组采用口服盐酸伐昔洛韦片联合口服匹多莫德片联合治疗，对照组单纯口服盐酸伐昔洛韦片治疗，疗程均2个月，随访6个月。结果：总体效果评价中，治疗组和对照组总有效率分别为97.8％、95.4％，两组疗效差异无显著性（P＞0.05），治疗组和对照组复发率分别为53.3％、90.7％，治疗组复发率明显低于对照组，差异有显著性（P＜0.01）。患者均未见明显不良反应。结论：口服盐酸伐昔洛韦片与口服匹多莫德片联合治疗复发性生殖器疱疹疗效好，且复发率明显低于单纯口服盐酸伐昔洛韦片，是治疗复发性生殖器疱疹较好的方法之一。
目的：評價口服鹽痠伐昔洛韋片聯閤口服匹多莫德片治療複髮性生殖器皰疹的臨床療效。方法：選擇複髮性生殖器皰疹患者88例，隨機分為兩組，治療組45例，對照組43例。治療組採用口服鹽痠伐昔洛韋片聯閤口服匹多莫德片聯閤治療，對照組單純口服鹽痠伐昔洛韋片治療，療程均2箇月，隨訪6箇月。結果：總體效果評價中，治療組和對照組總有效率分彆為97.8％、95.4％，兩組療效差異無顯著性（P＞0.05），治療組和對照組複髮率分彆為53.3％、90.7％，治療組複髮率明顯低于對照組，差異有顯著性（P＜0.01）。患者均未見明顯不良反應。結論：口服鹽痠伐昔洛韋片與口服匹多莫德片聯閤治療複髮性生殖器皰疹療效好，且複髮率明顯低于單純口服鹽痠伐昔洛韋片，是治療複髮性生殖器皰疹較好的方法之一。
목적：평개구복염산벌석락위편연합구복필다막덕편치료복발성생식기포진적림상료효。방법：선택복발성생식기포진환자88례，수궤분위량조，치료조45례，대조조43례。치료조채용구복염산벌석락위편연합구복필다막덕편연합치료，대조조단순구복염산벌석락위편치료，료정균2개월，수방6개월。결과：총체효과평개중，치료조화대조조총유효솔분별위97.8％、95.4％，량조료효차이무현저성（P＞0.05），치료조화대조조복발솔분별위53.3％、90.7％，치료조복발솔명현저우대조조，차이유현저성（P＜0.01）。환자균미견명현불량반응。결론：구복염산벌석락위편여구복필다막덕편연합치료복발성생식기포진료효호，차복발솔명현저우단순구복염산벌석락위편，시치료복발성생식기포진교호적방법지일。
Aim:To evaluate the clinical therapeutic efficacy of valaciclovir hydrochloride tablets in combination with pidotimod tablets in the treatment of recurrent genital herpes.Methods:Eighty-eight patients diagnosed and classified with recurrent genital herpes were randomly divided into two groups,the treatment group were 45 ,the control group were 43 .The treatment group received oral valaciclovir hydro-chloride tablets in combination with oral pidotimod tablets while control group received oral valaciclovir hydrochloride tablets only.A course of 2 months,follow-up of 6 months.Results:In the overall effect evaluation,the total effective rate in treatment group was 97.8%while the effective rate in control group was 95 .4%.The diffetence in effective rate between the two groups was not statistically significant(P>0.05 ).The recurrence rate in treatment group was 53.3%while the recurrence rate in control group was 90.7%,the recurrence rate in treatment group was significantly lower than in the control group,the dif-fetence in recurrence rate between the two groups were statistically significant(P<0.01 ).Conclusion:valaciclovir hydrochloride tablets in combination with pidotimod tablets is effective in the treatment of re-current genital herpes,the recurrence rate is lower than with oral valaciclovir hydrochloride tablets only, is one of the better method for treatment of recurrent genital herpes.
