CAJ | 학술논문

目的：探讨我院药物不良反应（ADR）发生的特点，为临床合理用药及药品安全性评价提供参考。方法：对我院2012年收集到的90例有效ADR报告进行统计分析。结果：90例ADR报告中，66例19～65岁患者发生ADR，占73.33％；静脉注射给药引发的ADR 43例，占47.78％；最易引起ADR的药物为中药制剂41例，占49.38％，其次为抗感染药物19例，占21.11％；ADR损害类型主要以皮肤及其附件损害为主（32例，占36％）；新的ADR 32例，主要为中药制剂引发；严重ADR9例，其中皮肤及其附件损害为6例。结论：临床应重视和加强ADR监测，合理用药，减少ADR的发生。
목적：탐토아원약물불량반응（ADR）발생적특점，위림상합리용약급약품안전성평개제공삼고。방법：대아원2012년수집도적90례유효ADR보고진행통계분석。결과：90례ADR보고중，66례19～65세환자발생ADR，점73.33％；정맥주사급약인발적ADR 43례，점47.78％；최역인기ADR적약물위중약제제41례，점49.38％，기차위항감염약물19례，점21.11％；ADR손해류형주요이피부급기부건손해위주（32례，점36％）；신적ADR 32례，주요위중약제제인발；엄중ADR9례，기중피부급기부건손해위6례。결론：림상응중시화가강ADR감측，합리용약，감소ADR적발생。
Objective: To explore the characteristics of adverse drug reactions (ADRs) in our hospital in order to provide reference for clinical rational use and safety evaluation of drugs. Methods:We collected 90 cases of ADRs reports in our hospital in 2012 and do statistical analysis. Results:ADRs occurred in 73.33%of patients(66 of 90) aged 19 to 65;ADRs caused by intravenous injection were 47.78% (43 of 90 cases) of patients; the most likely ADRs were caused by traditional Chinese medicines (41 cases, accounting for 49.38%), fol owed by anti nfective drugs (19 cases, 21.11%) ; the main types of ADRs were damage to the skin and its appendents (32 cases, accounting for 36%);There were 32 new ADRs which were mainly related with traditional Chinese medicines;There were 6 cases of damage to the skin and its appendents (66.67%) of 9 cases of serious ADRs . Conclusion: We should pay attention to and strengthen ADR monitoring and rational use of drugs for reducing or avoiding the occurrence of ADRs .