CAJ | 학술논문

格氏链球菌自溶酶AtlS是形成正常细胞壁结构和生物膜以及细菌自溶的关键蛋白。AtlS可调节细菌应激耐受力、生物膜形成和胞外DNA的释放，其表达是一个复杂的调节系统。本文除变异链球菌等口腔链球菌自溶酶外，重点就AtlS在格氏链球菌中的表达、信号转导通路及其相关调节研究进展作一综述。
격씨련구균자용매AtlS시형성정상세포벽결구화생물막이급세균자용적관건단백。AtlS가조절세균응격내수력、생물막형성화포외DNA적석방，기표체시일개복잡적조절계통。본문제변이련구균등구강련구균자용매외，중점취AtlS재격씨련구균중적표체、신호전도통로급기상관조절연구진전작일종술。
Streptococcus gordonii(S.gordonii)?AtlS?autolysin?plays?critical?roles?in?the?formation?of?normal?cell?walls,?development?of?biofilms,?and?production?of?autolysin.?The?expression?of?AtlS?is?subject?to?complex?regulation?and?modulates stress tolerance, biofilm formation, and extracellular DNA release. This study introduces the expression, two-component?systems,?and?related?regulatory?mechanisms?of?S.gordonii?AtlS?autolysis.