CAJ | 학술논문

目的应用二维斑点追踪成像（STI）评价肺动脉高压（PH）患者右心室功能，探讨PH对右心室功能的影响。方法65例PH患者，按肺动脉收缩压分为3组，其中PH轻度组25例，PH中度组22例，PH重度组18例；选取体检健康者30例为对照组。STI于心尖四腔切面测量右心室游离壁基底段、中间段及心尖段的纵向收缩期峰值应变（ε）、收缩期峰值应变率（SRs）、舒张早期峰值应变率（SRe）及舒张晚期峰值应变率（SRa）。结果 PH各组右室游离壁各节段ε、SRs、SRe、SRa均较对照组减低，差异有统计学意义（P<0.05）。PH各组间相应节段ε依次递减，有统计学差异（P<0.05），而SRs、SRe、SRa递减趋势不明显，差异无统计学意义（P>0.05）。结论 PH患者右心室功能减低，STI可较敏感而准确地评价右心室功能。
목적응용이유반점추종성상（STI）평개폐동맥고압（PH）환자우심실공능，탐토PH대우심실공능적영향。방법65례PH환자，안폐동맥수축압분위3조，기중PH경도조25례，PH중도조22례，PH중도조18례；선취체검건강자30례위대조조。STI우심첨사강절면측량우심실유리벽기저단、중간단급심첨단적종향수축기봉치응변（ε）、수축기봉치응변솔（SRs）、서장조기봉치응변솔（SRe）급서장만기봉치응변솔（SRa）。결과 PH각조우실유리벽각절단ε、SRs、SRe、SRa균교대조조감저，차이유통계학의의（P<0.05）。PH각조간상응절단ε의차체감，유통계학차이（P<0.05），이SRs、SRe、SRa체감추세불명현，차이무통계학의의（P>0.05）。결론 PH환자우심실공능감저，STI가교민감이준학지평개우심실공능。
Objective To assess right venticular function in patients with pulmonary hypertension by two-dimensional speckle tracking imaging ( 2D-STI ) , and study the effect of the pulmonary hypertension on right ventricular function . Methods According to pulmonary artery systolic pressure,65 patients with pulmonary hypertension were divided into mild(n=25), moderate(n=22) and severe(n=18) groups. 30 healthy controls were in the contrast group. Longitudinal peak systolic strain(ε)and strain rate(SRs),early diastolic strain rate(SRe) and late diastolic strain rate(SRa) were measured in right ventricular free wall for basal,mid and apical segment in 65 patients with pulmonary hypertension and 30 healthy controls by 2D-STI from the apical four-chamber view. Results ε,SRs,SRe and SRa were obviously decreased in the mild,moderate and severe pulmonary hypertension groups compared with contrast group (P < 0.05). ε of all segements in mild,moderate and severe pulmonary hypertension groups were reduced progressively (P < 0.05),while SRs,SRe and SRa did not follow the same trendency as longitudinal peak systolic strain (P>0.05). Conclusion Right ventricular function in patients with pulmonary hypertension is impaired. Right ventricular function can be assessed with 2D-STI accurately and sensitively.