临床超声医学杂志
臨床超聲醫學雜誌
림상초성의학잡지
JOURNAL OF ULTRASOUND IN CLINICAL M，EDICINE
2013年
8期
540-544
,共5页
超声检查%造影剂%乳腺肿瘤,良恶性
超聲檢查%造影劑%乳腺腫瘤,良噁性
초성검사%조영제%유선종류,량악성
Ultrasonography%Contrast agent%Breast neoplasms,benign and malignant
目的探讨乳腺良恶性肿瘤超声造影灌注曲线的特点及临床价值。方法87例乳腺肿瘤患者分为恶性组57例和良性组30例，Sonolver软件获取其超声造影图像，定量分析其分析区和参考区灌注曲线参数。结果与良性组分析区比较，恶性组分析区上升时间（RT）、达峰时间（TTP）及平均渡越时间（mTT）均减小，上升斜率（RS）和下降斜率（DS）均增大（P<0.05）；恶性组分析区RT、TTP及mTT的95%可信区间均减小（P<0.05）。与良性组参考区比较，恶性组参考区RT减小，RS和DS增大（P<0.05）。乳腺良性和恶性肿瘤分析区RT、TTP及mTT小于参考区，分析区峰值强度RS、DS及拟合优度大于参考区，差异均有统计学意义（P<0.05）。结论乳腺肿瘤的灌注参数可评估肿瘤内的血流灌注，为乳腺良恶性肿瘤的诊断提供了新的定量指标。
目的探討乳腺良噁性腫瘤超聲造影灌註麯線的特點及臨床價值。方法87例乳腺腫瘤患者分為噁性組57例和良性組30例，Sonolver軟件穫取其超聲造影圖像，定量分析其分析區和參攷區灌註麯線參數。結果與良性組分析區比較，噁性組分析區上升時間（RT）、達峰時間（TTP）及平均渡越時間（mTT）均減小，上升斜率（RS）和下降斜率（DS）均增大（P<0.05）；噁性組分析區RT、TTP及mTT的95%可信區間均減小（P<0.05）。與良性組參攷區比較，噁性組參攷區RT減小，RS和DS增大（P<0.05）。乳腺良性和噁性腫瘤分析區RT、TTP及mTT小于參攷區，分析區峰值彊度RS、DS及擬閤優度大于參攷區，差異均有統計學意義（P<0.05）。結論乳腺腫瘤的灌註參數可評估腫瘤內的血流灌註，為乳腺良噁性腫瘤的診斷提供瞭新的定量指標。
목적탐토유선량악성종류초성조영관주곡선적특점급림상개치。방법87례유선종류환자분위악성조57례화량성조30례，Sonolver연건획취기초성조영도상，정량분석기분석구화삼고구관주곡선삼수。결과여량성조분석구비교，악성조분석구상승시간（RT）、체봉시간（TTP）급평균도월시간（mTT）균감소，상승사솔（RS）화하강사솔（DS）균증대（P<0.05）；악성조분석구RT、TTP급mTT적95%가신구간균감소（P<0.05）。여량성조삼고구비교，악성조삼고구RT감소，RS화DS증대（P<0.05）。유선량성화악성종류분석구RT、TTP급mTT소우삼고구，분석구봉치강도RS、DS급의합우도대우삼고구，차이균유통계학의의（P<0.05）。결론유선종류적관주삼수가평고종류내적혈류관주，위유선량악성종류적진단제공료신적정량지표。
Objective To study the perfusion curve characteristics and the clinical value of contrast-enhanced ultrasound (CEUS) in benign and malignant breast tumors. Methods The CEUS images of 87 patients with breast tumors were analyzed by the off-line Sonolver software,the perfusion curve parameters of analysis area and reference area were received and and quantitatively analyzed. The results were compare with those of pathology. the characteristics of CEUS and perfusion curve of breast benign and malignant tumors were analyzed. Results Compared with benign breast tumors, rise time (RT), time to peak (TTP),mean trasit time( mTT) of malignant breast tumors were significantly shorter and rise slope( RS), descending slope(DS) were increased in analysis area (P<0.05). The 95%CI of RT,TTP,mTT were significantly decreased in analysis area of malignant tumors (P<0.05). RT was shorter, RS and DS were increased in reference area of malignant tumors (P<0.05). For benign and malignant tumors,The RT, TTP and mTT in analysis area were shorter than those in reference area. the IMAX, RS, DS, QOF of analysis area were higher than those of reference area, there was significant difference (P < 0.05). Conclusion Perfusion parameters of breast tumor evaluated by CEUS can assess blood perfusion within the tumor, it provides a new quantitative indicator for diagnosis of breast benign and malignant tumors.
